Metabolism and Epigenetic Regulation: Implications in Cancer

Part 1: Regulation Of Key Metabolic Pathways In Cancer.- Chapter 1: Reprogramming Carbohydrate Metabolism In Cancer And Its Role In Regulating The Tumor Microenvironment. Chapter 2: Iron In Cancer Progression: Does Bach1 Promote Metastasis By Altering Iron Homeostasis?.- Chapter 3: Regulation Of Lipid Metabolism Under Stress And Its Role In Cancer.- Chapter 4: Role Of The Histone Acetyl Transferase Mof And The Histone Deacetylase Sirtuins In Regulation Of H4k16ac During Dna Damage Repair And Metabolic Programming: Implications In Cancer And Aging.- Chapter 5: Autophagy In Cancer: A Metabolic Perspective.- Part 2: Epigenetic Regulation Of Cellular Metabolic Pathways.- Chapter 6: Long Noncoding Rnas; Lnc(Ing) Rna Metabolism, To Cancer Biology.- Chapter 7: Modulation Of Dna/Rna Methylation Signalling Mediating Metabolic Homeostasis In Cancer.- Chapter 8:  Nutritional Epigenetics: How Metabolism Epigenetically Controls Cellular Physiology, Gene Expression And Disease.- Chapter 9: Epigenetic Reprogramming Of The Glucose Metabolic Pathways By The Chromatin Effectors During Cancer.- Chapter 10: Sirtuin 6 Is A Critical Epigenetic Regulator Of Cancer.- Chapter 11: Epigenetic Regulation During Hypoxia And Its Implications In Cancer.- Part 3: Epigenetic Regulation In Cancer.- Chapter 12: Metabolic Regulation Of Lysine Acetylation: Implications In Cancer.- Chapter 13: The Cross-Talk Between Epigenetic Gene Regulation And Signaling Pathways Regulates Cancer Pathogenesis.- Chapter 14: Epigenetic Regulation Towards Acquired Drug Resistance In Cancer.- Chapter 15: Structural Basis Of Targeted Imaging And Therapy In Cancer- Explorations With The Epigenetic Drugs.- Chapter 16: Epigenetic Small Molecule Modulators Targeting Metabolic Pathways In Cancer.- Chapter 17: Modulation Of Dna/Rna Methylation By Small Molecule Modulators And Their Implications In Cancer.- Chapter 18: Understanding The Cross-Talk Between Epigenetics And Immunometabolism To Combat Cancer.



 

At present Dr. Tapas K Kundu, is the Director of CSIR-Central Drug Research Institute, Lucknow, India.  He obtained his PhD from the Indian Institute of Science, Bangalore, in the year 1995. Following his PhD, he had a short stint as a visiting foreign research associate in the National Institute of Genetics, Mishima, Japan, followed by a post-doctoral fellowship at the Rockefeller University, USA. He joined JNCASR, Bangalore in 1999 and became full Professor in 2009. He was a visiting Professor of ENS De Lyon, France and National University of Singapore.  Dr. Kundu has made significant contributions in the area of regulation of gene expression and its link to disease and therapeutics. He is not only elucidating the mechanisms of transcription regulation through the epigenetic modifications, but also targeting them to design new generation diagnostics, as well as therapeutics. Over the years, he has published several research papers in many international journals and also edited two books on Epigenetics. Several patent applications from the laboratory have been granted and some are under process, which includes a few academically important research reagents with potential commercial values, some of which have already been commercialized by renowned companies. He is the recipient of several awards, noteworthy among which are: The Shanti Swarup Bhatnagar prize from CSIR, Government of India, the National Academy of Science, India- Reliance Industries Platinum Jubilee Award, the Sir JC Bose National Fellowship from DST, the GD Birla award for scientific research. He is the fellow of three major national academies of India and served as an editorial board member of the Journal of Biological Chemistry (JBC). He was instrumental to establish the Asian Forum for Chromatin and Chromosome Biology and Chemical Biology Society, India (CBS I). At present he is the President of CBS I. Dr. Kundu is serving