The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies / Medical Radiology (PDF)
This book provides an overview of the fundamentals of tumor biology and the influence of various biologic factors, including inhomogeneity of cancer cells, microenvironment, and host factors, on the design of therapeutic strategies and the outcome of...
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This book provides an overview of the fundamentals of tumor biology and the influence of various biologic factors, including inhomogeneity of cancer cells, microenvironment, and host factors, on the design of therapeutic strategies and the outcome of established and emerging treatments. Particular attention is devoted to multidisciplinary combined modality therapy. The topics reviewed include tumorigenesis, cell proliferation, angiogenesis, physiology of malignant tissues, adhesion and invasion, development of metastases, and the role of the immune system in cancer development. Subsequent chapters focus on cancer prevention, detection, and treatment. The principles of chemotherapy, radiotherapy, and molecularly targeted therapy are discussed, treatment resistance is explained, and strategies for rational combinations are provided, including the design of translational studies. Furthermore, the principles and clinical implications of new diagnostic and therapeutic approaches, such as gene expression profiling, gene transfer and silencing, proteomics, and molecular imaging, are presented. The chapters in this book have been written by an outstanding group of basic scientists, clinical researchers, and cancer professionals with long experience in the field. Their aim is to educate and inspire all those who devote most of their work to research into cancer and its treatment.
M. Molls, Professor, Chairman of the Department of Radiation Oncology, Klinikum rechts der Isar der TU Muenchen, Germany
C. Nieder, Professor at the University of Tromsø, Norway, Oncologist
M Anscher, Professor and Chairman, Department of Radiation Oncology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA
- 2009, 2009, 367 Seiten, Englisch
- Herausgegeben: Michael Molls, Peter Vaupel, Carsten Nieder, Mitchell Steven Anscher
- Verlag: Springer-Verlag GmbH
- ISBN-10: 3540743863
- ISBN-13: 9783540743866
- Erscheinungsdatum: 25.03.2009
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- Grösse: 8.75 MB
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