The Future of HIV-1 Therapeutics / Current Topics in Microbiology and Immunology Bd.389 (PDF)
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This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike.
- 2015, 2015, 254 Seiten, Englisch
- Herausgegeben: Bruce E. Torbett, David S. Goodsell, Douglas D. Richman
- Verlag: Springer-Verlag GmbH
- ISBN-10: 3319185187
- ISBN-13: 9783319185187
- Erscheinungsdatum: 22.04.2015
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- Grösse: 6.81 MB
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“This book includes 8comprehensive, heavily referenced chapters on antiretroviral drug development.… a comprehensive, readable review of a subject that brings together 2 or moredecades of molecular virology research and drug development. … the chapters inthis book are likely to be, for the next several years, highly useful andpopular starting points for learning about new areas in HIV drug development.”(Robert W. Shafer, Clinical Infectious Diseases, September, 2015)
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