The Functional Nucleus (PDF)
(Sprache: Englisch)
This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the...
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This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.
Autoren-Porträt
David P. Bazett-JonesThe Hospital for Sick Children, Toronto, ON, Canada Graham DellaireDalhousie University, Halifax, NS, Canada
Bibliographische Angaben
- 2016, 1st ed. 2016, 513 Seiten, Englisch
- Herausgegeben: David P. Bazett-Jones, Graham Dellaire
- Verlag: Springer-Verlag GmbH
- ISBN-10: 3319388827
- ISBN-13: 9783319388823
- Erscheinungsdatum: 17.10.2016
Abhängig von Bildschirmgrösse und eingestellter Schriftgrösse kann die Seitenzahl auf Ihrem Lesegerät variieren.
eBook Informationen
- Dateiformat: PDF
- Grösse: 10 MB
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Sprache:
Englisch
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