Textbook of Personalized Medicine (PDF)

Personalized medicine is the concept that selection of a treatment should be tailored according to the individual patient's specific characteristics, including age, gender, height/weight, ethnicity, diet,  and environment , versus a decision based on 'standards of care' derived by averaging responses across large cohorts of individuals in clinical trials. This alternate approach has only been possible as a result of the translation and integration of several new technologies in clinical care. As the first definitive work on this topic, Textbook of Personalized Medicine reviews  the  fundamentals and development of personalized medicine,  and subsequent adoptions of the concepts by the  biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues. The textbook will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries, and interested members of the public.

Contents:
Basics of Personalized Medicine
Molecular Diagnostics as Basis of Personalized Medicine
Role of Biomarkers in Personalized Medicine
Pharmacogenetics
Pharmacogenomics
Pharmacoproteomics
Metabolomics
Personalized Biological Therapies
Development of Personalized Therapy
Personalized Therapy of Cancer
Personalized Management of Cardiovascular Disorders
Personalized Management of Miscellaneous Disorders
Personalized preventive medicine
Organization of Personalized Medicine
Ethical and Regulatory Aspects of Personalized Medicine
Economics of Personalized Medicine
Future of Personalized Medicine

About the Author

Professor K. K. Jain is trained in neurosurgery with specialist qualifications. He worked for 25 years in various academic positions and private practice worldwide mostly in Canada and the US. His clinical research interests during these years were use of lasers for microneurosurgery and hyperbaric oxygen. He has been involved in biotechnology since 1989, when he moved to Basel, Switzerland. He was elected a fellow of the Faculty of Pharmaceutical Medicine of the Royal Colleges of UK in 2000. He is the author of over 405 publications including 15 books and 48 special reports. Important books are Textbook of Gene Therapy, Textbook of Hyperbaric Medicine and Handbook of Nanomedicine. He is a member of editorial board of several journals and senior associate editor of MedLink Neurology (San Diego, California), a continuing education program for neurologists. Prof. Jain has been interested in integrating various biotechnologies to develop personalized medicine since 1997. He wrote the first report on personalized medicine, which was published in 1998 by Decision Resources Inc. The report titled Personalized Medicine: scientific and commercial aspects is continuously updated and published at Jain PharmaBiotech, Basel. He lectures and conducts workshops worldwide.