System Engineering Approach to Planning Anticancer Therapies (PDF)
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The book begins with an analysis of cell cycle control, moving on to control effects on cell population and structured models and finally the signaling pathways involved in carcinogenesis and their influence on therapy outcome. It also discusses the incorporation of intracellular processes using signaling pathway models, since the successful treatment of cancer based on analysis of intracellular processes, might soon be a reality. It brings together various aspects of modeling anticancer therapies, which until now have been distributed over a wide range of literature. Written for researchers and graduate students interested in the use of mathematical and engineering tools in biomedicine with special emphasis on applications in cancer diagnosis and treatment, this self-contained book can be easily understood with only a minimal basic knowledge of control and system engineering methods as well as the biology of cancer. Its interdisciplinary character and the authors' extensive experience in cooperating with clinicians and biologists make it interesting reading for researchers from control and system engineering looking for applications of their knowledge. Systems and molecular biologists as well as clinicians will also find new inspiration for their research.
Marek Kimmel is a Professor of Statistics and Bioengineering at the Rice University in Houston, TX, USA and a Professor in the Systems Engineering Group in the Silesian University of Technology in Gliwice, Poland. He is an author and co-author of over 200 peer-reviewed publications and 5 monographs. His professional interests are focused in application of stochastic processes in molecular and cell biology and genetics. He advised about 30 doctoral students in USA, Poland and France. His research has been supported by grants from NSF, NIH, NATO, ERC, NCN (Polish National Science Committee), EPSRC (UK). He is the Mathematical Biology Editor of Biology Direct and in 2011 was the Fellow at the Institute for Advanced Study at Warwick University, UK. He is a Fellow of the American Statistical Association.
Jaroslaw Smieja received PhD degree in Automatic
Krzysztof Psiuk-Maksymowicz obtained his PhD degree in Biocybernetics and Medical Engineering from Silesian University of Technology, Gliwice Poland, in 2009. He works as an assistant professor at Institute of Automatic Control of Silesian University of Technology. In 2004-2007 he worked as a young research scientist in the Department of Physics, Gothenburg University, Sweden. His research focuses on mathematical biology, in particular modeling of tumor growth and therapeutic actions, as well as medical image processing. He has published over 30 papers in journals and refereed conference proceedings. He took part in many national and international projects, focused on either basic research, applications or software development.
Krzysztof Puszynski received his M. Sc degree in automatic control and robotics from Silesian University of Technology in 2003 and Ph.D. in biocybernetics and biomedical engineering also from Silesian University of Technology in 2009. His main research interests include systems biology, bioinformatics and control engineering in biological systems. He was a visiting professor in the Institute of the Systems Analysis and Informatics in Rome in 2011 and University of Alberta in Edmonton, Canada in 2012. He is presently an Assistant Professor in the Department of Automatic Control at the Silesian University of Technology. He is an author or co-author of more than 50 journal articles, book chapters and conference papers.
- Autoren: Andrzej Swierniak , Marek Kimmel , Jaroslaw Smieja , Krzysztof Puszynski , Krzysztof Psiuk-Maksymowicz
- 2016, 1st ed. 2016, 235 Seiten, Englisch
- Verlag: Springer-Verlag GmbH
- ISBN-10: 3319280953
- ISBN-13: 9783319280950
- Erscheinungsdatum: 19.05.2016
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- Grösse: 4.78 MB
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