Rare Kidney Tumors (PDF)
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This book provides clinicians with clear guidance on treatment decision-making in patients with rare kidney cancers. After a brief review on epidemiology, pathology, and biology, each chapter focuses on the multidisciplinary management of a particular tumor subtype using the full range of available cancer therapy modalities, including surgery, radiotherapy, chemotherapy, targeted therapies, and immunotherapy. Emerging therapies and future directions in the management of each cancer subtype are also discussed. The chapters are all written by multidisciplinary teams of international experts comprising at least a urologist, a medical oncologist, and a pathologist.
Rare kidney cancers represent 15% of renal cell carcinomas. In comparison with clear cell renal cell carcinomas, little is known about the biology of such cancers, and few trials have reported on the efficacy of targeted therapies in the metastatic setting. Optimal management thus poses significant challenges and often requires a multidisciplinary team. This book will be an ideal reference guide for all clinicians involved in the care of patients with these orphan tumors.
Dr. Gabriel G. Malouf, is professor of medical oncology in Strasbourg University and researcher at the Institute of Genetics and Molecular and Cellular Biology (IGBMC). A staff member of the department of medical oncology, Dr Malouf's clinical and translational research focus on genitourinary malignancies.
Doctor Malouf earned a medical degree at the University of Paris Descartes (2012). After completing a residency program in medical oncology, Dr Malouf was postdoctoral postdoctoral follow at MD Anderson cancer center. After returning to Paris, Dr Malouf earned a PhD in cancer epigenetics (2014). Dr Malouf developed an expertise in rare kidney cancers, especially translocation renal cell carcinoma, medullary renal cell carcinomas and collecting duct carcinomas. Dr Malouf published more than 50 original papers in high-impact journals such as Clinical Cancer Research, Cancer Research and Genome Biology. In addition, Dr Malouf serve as faculty member for main meetings such as ASCO Genitourinary and EMUC (European Multidisciplinary Meeting on Urological Cancers) meetings. Dr Malouf is the coordinator of the research programs at the medical oncology department. His current focus is to develop a translational research program focusing on deciphering genetic and epigenetic aberrations of rare genitourinary malignancies.
Dr. Nizar M. Tannir, is Professor and Deputy Chair of the Department of Genitourinary Medical Oncology at MD Anderson Cancer Center, and is a clinical investigator with expertise in trial design. Dr. Tannir has conducted numerous clinical trials in renal cell carcinoma (RCC), and is an expert on rare kidney cancers, particularly, translocation RCC (Xp11.2) and renal medullary carcinoma (RMC). He co-chairs a think-tank on RMC, bringing together world experts from different fields to accelerate discovery and novel therapeutics for this devastating orphan cancer. Dr. Tannir has authored more than 150
- 2018, 1st ed. 2019, 128 Seiten, Englisch
- Herausgegeben: Gabriel G. Malouf, Nizar M. Tannir
- Verlag: Springer-Verlag GmbH
- ISBN-10: 3319969897
- ISBN-13: 9783319969893
- Erscheinungsdatum: 29.09.2018
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- Grösse: 2.79 MB
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