Proteomics in Drug Research / Methods and Principles in Medicinal Chemistry Bd.28 (PDF)
(Sprache: Englisch)
From skillful handling of the wide range of technologies to successful applications in drug discovery -- this handbook has all the information professional proteomics users need.
Edited by experts working at one of the hot spots in European proteomic...
Edited by experts working at one of the hot spots in European proteomic...
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From skillful handling of the wide range of technologies to successful applications in drug discovery -- this handbook has all the information professional proteomics users need.
Edited by experts working at one of the hot spots in European proteomic research, the numerous contributions by experts from the pharmaceutical industry and public proteomics consortia to provide the necessary perspective on current trends and developments in this exciting field.
Following an introductory chapter, the book moves on to proteomic technologies, such as protein biochips, protein-protein interactions, and proteome analysis in situ. The section on applications includes bioinformatics, Alzheimer's disease, neuroproteomics, plasma and T-cell proteomics, differential phosphoproteome analysis and biomarkers, as well as pharmacogenomics.
Invaluable reading for medicinal and pharmaceutical chemists, gene technologists, molecular biologists, and those working in the pharmaceutical industry.
Edited by experts working at one of the hot spots in European proteomic research, the numerous contributions by experts from the pharmaceutical industry and public proteomics consortia to provide the necessary perspective on current trends and developments in this exciting field.
Following an introductory chapter, the book moves on to proteomic technologies, such as protein biochips, protein-protein interactions, and proteome analysis in situ. The section on applications includes bioinformatics, Alzheimer's disease, neuroproteomics, plasma and T-cell proteomics, differential phosphoproteome analysis and biomarkers, as well as pharmacogenomics.
Invaluable reading for medicinal and pharmaceutical chemists, gene technologists, molecular biologists, and those working in the pharmaceutical industry.
Inhaltsverzeichnis zu „Proteomics in Drug Research / Methods and Principles in Medicinal Chemistry Bd.28 (PDF)“
INTRODUCTION Administrative Optimization of Proteomics Networks for Drug Development Proteomic Data Standardization, Deposition and Exchange PROTEOMIC TECHNOLOGIES Difference Gel Electrophoresis (DIGE): the Next Generation of Two-Dimensional Gel Electrophoresis for Clinical Research Biological Mass Spectrometry: Basics and Drug Discovery Related Approaches Multidimensional Column Liquid Chromatography (LC) in Proteomics Peptidomics Technologies and Applications in Drug Research Protein Biochips in the Proteomic Field Current Developments for the In Vitro Characterization of Protein Interactions APPLICATIONS Molecular Networks in Morphologically Intact Cells and Tissue-Challenge for Biology and Drug Development From Target to Lead Synthesis Differential Phosphoproteome Analysis in Medical Research Biomarker Discovery in Renal Cell Carcinoma Applying Proteome-Based Studies in Combination with Serology Studies of Drug Resistance Using Organelle Proteomics Clinical Neuroproteomics of Human Body Fluids: CSF and Blood Assays for Early and Differential Diagnosis of Dementia Proteomics in Alzheimer's Disease Cardiac Proteomics Innovation Processes
Autoren-Porträt
All six editors are Researchers at the Medical Proteom-Center hosted by the University of Bochum (Germany). This international research center was established in 2002 under the leadership of Helmut E. Meyer, a co-founder of the Protagen AG. Professor Meyer is also initiator and coordinator of the Human Brain Proteome Project within the German National Genome Research Net (NGFN) as well as of the Brain Proteome Project within the Human Proteome Organisation (HUPO BPP).
Bibliographische Angaben
- 2006, 1. Auflage, 362 Seiten, Englisch
- Herausgegeben: Michael Hamacher, Katrin Marcus, Kai Stühler, Andre Van Hall, Bettina Warscheid, Helmut E. Meyer
- Verlag: Wiley-VCH GmbH
- ISBN-10: 3527607943
- ISBN-13: 9783527607945
- Erscheinungsdatum: 21.08.2006
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