MRI of Tissues with Short T2s or T2*s (PDF)

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Up to now MRI could not be used clinically for imaging fine
structures of bones or muscles. Since the late 1990s however, the
scene has changed dramatically. In particular, Graeme Bydder and
his many collaborators have demonstrated the possibility -
and importance - of imaging structures in the body that were
previously regarded as being "MR Invisible". The images
obtained with a variety of these newly developed methods exhibit
complex contrast, resulting in a new quality of images for a wide
range of new applications.

This Handbook is designed to enable the radiology community to
begin their assessment of how best to exploit these new
capabilities. It is organised in four major sections - the
first of which, after an Introduction, deals with the basic science
underlying the rest of the contents of the Handbook. The second,
larger, section describes the techniques which are used in
recovering the short T2 and T2* data from which the images are
reconstructed. The third and fourth sections present a range of
applications of the methods described earlier. The third section
deals with pre-clinical uses and studies, while the final section
describes a range of clinical applications. It is this last section
that will surely have the biggest impact on the development in the
next few years as the huge promise of Short T2 and T2* Imaging will be exploited to the benefit of patients.

In many instances, the authors of an article are the only
research group who have published on the topic they describe. This
demonstrates that this Handbook presents a range of methods and
applications with a huge potential for future developments.

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