Hydrophilic Matrix Tablets for Oral Controlled Release / AAPS Advances in the Pharmaceutical Sciences Series Bd.16 (PDF)
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This detailed volume addresses key issues and subtle nuances involved in developing hydrophilic matrix tablets as an approach to oral controlled release. It brings together information from more than five decades of research and development on hydrophilic matrix tablets and provides perspective on contemporary issues. Twelve comprehensive chapters explore a variety of topics including polymers (hypromellose, natural polysaccharides and polyethylene oxide) and their utilization in hydrophilic matrices, critical interactions impacting tablet performance, in vitro physical and imaging techniques, and microenvironmental pH control and mixed polymer approaches, among others. In one collective volume, Hydrophilic Matrix Tablets for Oral Controlled Release provides a single source of current knowledge, including sections of previously unpublished data. It is an important resource for industrial and academic scientists investigating and developing these oral controlled release formulations.
Samuel Pygall is currently an Associate Director and Patient Services Manager at MSD U.K. He was awarded a Master of Pharmacy and a PhD in Pharmaceutical Science from the University of Nottingham in the U.K. Dr. Pygall has a core interest in fostering collaboration between academia and industry to form innovative patient-centric healthcare solutions. He holds a visiting lecturer position at Aston School of Pharmacy in the U.K. and is a U.K.-registered pharmacist, member of the Royal Pharmaceutical Society of Great Britain and past committee member of the United Kingdom and Ireland Controlled Release Society (UKICRS).
Colin Melia is Associate Professor at the School of Pharmacy, University of Nottingham, U.K. He has widely published, provided expert opinions on modified release dosage forms and has been engaged in collaborative research and consultancy with some sixty pharmaceutical and allied companies worldwide. His research group, Formulation Insights, focuses on the elucidation of drug release mechanisms that underlie modifiedrelease behaviour. At Nottingham University, he
- 2014, 2014, 326 Seiten, Englisch
- Herausgegeben: Peter Timmins, Samuel R. Pygall, Colin D. Melia
- Verlag: Springer-Verlag GmbH
- ISBN-10: 1493915193
- ISBN-13: 9781493915194
- Erscheinungsdatum: 11.10.2014
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- Grösse: 8.20 MB
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