Essential Aspects of Immunometabolism in Health and Disease (PDF)
Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although...
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Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases.
The edited volume Essentials aspects of Immunometabolism will give the readers a broad view on how metabolic pathways can influence many types of immune cells during activation, differentiation and function, in health and disease. Of note, the structure of the book was created thinking not only on the experienced immunologist but also on undergraduate and graduate students, physicians, and all members of the scientific community interested in this exciting field of research.
Prof. Andrade-Oliveira is a biologist interested in studying the immunometabolism at the host-microorganisms interaction. He completed his PhD in immunology at University of Sao Paulo with a trainee period at Johns Hopkins University where he experienced the study of the metabolism of T cells. He is an ex-PEW Latin American Fellow at NIAID/NIH where he studied the role of host metabolism after acute gastrointestinal infections. Currently, he is head of the Immunometabolism at host-microorganism interactions at the UFABC where his mainly interests are immunometabolism of immune cells, microbiota, infections and host physiology.
Pedro M M Moraes Vieira is a doctor of veterinary medicine by the University of Brasilia and a PhD in immunology by the University of Sao Paulo. Currently he is Associated Professor of Immunology at the University of
Jose C. Alves-Filho is a Pharm D. with BS degree in Biochemistry. He received his PhD in Pharmacology from the University of São Paulo. Afterwards, he spent three years as a Postdoctoral Fellow in the Institute of Infection, Immunity & Inflammation at the University of Glasgow. Currently, he is an Assistant Professor of Immunopharmacology in the Ribeirão Preto Medical School at University of São Paulo and head of the Laboratory of Immunoregulation. His research interest is focused in understanding how cellular metabolism affects the plasticity and function of immune cells, mainly T lymphocytes, and its impact on the outcome of chronic inflammatory diseases. He has more than 120 publications in peer-reviewed journals and several PhD students and Postdoctoral Fellows conducting projects under his supervision.
- 2021, 1st ed. 2022, 278 Seiten, Englisch
- Herausgegeben: Niels Olsen Saraiva Camara, Jose C Alves-Filho, Pedro Manoel Mendes de Moraes-Vieira, Vinicius Andrade-Oliveira
- Verlag: Springer International Publishing
- ISBN-10: 303086684X
- ISBN-13: 9783030866846
- Erscheinungsdatum: 21.10.2021
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- Grösse: 5.54 MB
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