Co-signal Molecules in T Cell Activation / Advances in Experimental Medicine and Biology Bd.1189 (PDF)
Immune Regulation in Health and Disease
(Sprache: Englisch)
This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. The first part of the book is devoted to...
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This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. The first part of the book is devoted to co-signal molecules and the regulation of T cells. Following an initial overview, subsequent chapters examine each co-signal molecule in turn and discuss the mechanisms by which co-signal molecules regulate the different types of T cell. The second part covers various clinical applications, including in autoimmune disease, neurological disorders, transplantation, graft-versus-host disease, and cancer immunotherapy. To date, co-stimulation blockade and co-inhibition blockade have shown beneficial effects and many additional clinical trials targeting co-signal molecules are ongoing. The mechanisms underlying these successful treatments are explained and the future therapeutic potential in the aforementioned diseases is evaluated. Co-signal Molecules in T Cell Activation will be a valuable reference guide to co-stimulation for basic and clinical researchers in the fields of both immunology and pharmaceutical science.
Autoren-Porträt
Miyuki AzumaTokyo Medical and Dental University, Grad Sch of Medical and Dental Sciences, JapanHideo YagitaJuntendo University School of Medicine, Dept of Immunology, Japan
Bibliographische Angaben
- 2019, 1st ed. 2019, 326 Seiten, Englisch
- Herausgegeben: Miyuki Azuma, Hideo Yagita
- Verlag: Springer-Verlag GmbH
- ISBN-10: 9813297174
- ISBN-13: 9789813297173
- Erscheinungsdatum: 22.11.2019
Abhängig von Bildschirmgrösse und eingestellter Schriftgrösse kann die Seitenzahl auf Ihrem Lesegerät variieren.
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- Dateiformat: PDF
- Grösse: 6.82 MB
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Sprache:
Englisch
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