Animal Models in Research (PDF)

peer-reviewed publications, and over 8 book chapters. His current area of interest is refinement of animal models and refinement of rodent care, handling, and housing standards.

Dr. Satish Patel is working as general manager and head of Animal Research Facilities, Zydus Research Centre, Ahmedabad, Gujarat, India. He is a veterinarian and done his Ph.D in veterinary pharmacology and toxicology from Anand Agricultural University, Gujarat, India. He has been working with laboratory animals for more than 24 years. He has performed key role in establishing many laboratory animal facilities at different organizations, and among these few are GLP and AAALAC accredited. As part of research and development activities that he is leading in Zydus Research Centre, he travels and works with many foreign CROs in the USA, Canada, and Europe for preclinical studies including veterinary Bio availability and Bio equivalence studies. He has also developed many preclinicaldisease models, in different therapeutic areas like diabetes, inflammation, arthritis, dyslipidemia, cancer etc. using different novel methodologies and techniques. He has enormous knowledge and experience in care, management, breeding and regulatory experimentation of laboratory animals including inbreds, outbreds, mutants, transgenics (genetically modified), immune-deficient and humanized animal models, dogs and non-human primates. He has also to his credit, a few innovative products which are commercialized and, are in the market, where he has been involved in basic research and development. He also worked for B.V. Patel Pharmaceutical Education Research & Development (B.V. PERD) Centre, Hester Bioscience ltd, and Cadila Pharmaceutical Pvt ltd, Ahmedabad in the field of biomedical research and development. He has undergone several training programs on laboratory animal management, health monitoring and animal model development. He served as a working group member to revise the syllabus for minimum standards for veterinary practice regulations for laboratory animals formed by The Veterinary Council of India (VCI), a statutory body. He has published more than 25 research publications in national and international peer-reviewed journals. He is also member of few societies of veterinary science and laboratory animal science. His current area of interest is improvement of current practices of laboratory animal care and management and refining methodologies in animal experimentation.



Dr. Perumal Nagarajan is working as head, scientist at laboratory animal facility, National Institute of Immunology, New Delhi, India. Being a veterinarian, he has been working on laboratory animals for more than 20 years. He has vast knowledge and expertise in the care, management, breeding and medicine of laboratory animals including genetically modified animals, immunodeficient animal models, humanized animal models and non-human primates that are beingused in research. Before joining NII, he worked at Central Drug Research Institute (CDRI) and the National University of Singapore (NUS). He had undergone diverse training in laboratory animals including imaging modalities and microsurgery abroad. His research interest is in animal models for various diseases and in particular metabolic diseases. He has published more than 50 research articles in peer-reviewed international journals authored book chapters and edited the book "Essentials of Laboratory Animal Science: Principles and Practices" Springer. He is also serving as a reviewer for various international journals and he is a member of several national and international scientific societies related to laboratory animal science.