Trinucleotide Repeats

Experimenting with Trinucleotide Repeats: Facts and Technical Issues.- Fast Assays to Detect Interruptions in CTG.CAG Repeat Expansions.- Tracking Expansions of Stable and Threshold Length Trinucleotide Repeat Tracts In Vivo and In Vitro Using Saccharomyces cerevisiae.- Quantifying Replication Fork Progression at CTG Repeats by 2D Gel Electrophoresis.- Genetic Assays to Study Repeat Fragility in Saccharomyces cerevisiae.- Genetic Screens to Study GAA/TTC and Inverted Repeat Instability in Saccharomyces cerevisiae.- Monitoring Double-Strand Break Repair of Trinucleotide Repeats Using a Yeast Fluorescent Reporter Assay.- Analysis of Trinucleotide Repeat Stability by Integration at a Chromosomal Ectopic Site.- Experimental System to Study Instability of (CGG)n Repeats in Cultured Mammalian Cells.- Assessing Triplet Repeat Expansions in Human SVG-A Cell Culture.- The Isolation and Analysis of the CGG-Repeat Size in Male and Female Gametes from a Fragile X Mouse Model.- In Vitro Synthesis and RNA Structure Probing of CUG Triplet Repeat RNA.- FISH Protocol for Myotonic Dystrophy Type 1 Cells.- Real Time Videomicroscopy and Semi-Automated Analysis of Brain Cell Culture Models of Trinucleotide Repeat Expansion Diseases.- Primary Cultures of Pure Embryonic Dorsal Root Ganglia Sensory Neurons as a New Cellular Model for Friedreich's Ataxia.- GFP Reporters to Monitor Instability and Expression of Expanded CAG/CTG Repeats.- Gene Therapy for Huntington's Disease Using Targeted Endonucleases.