Toxicology in Transition

stating the problem.- Prenatal exposure to marihuana and tobacco during infancy, early and middle childhood: effects and an attempt at synthesis.- Delayed developmental neuro-and immunotoxicity of benzodiazepines.- Changes of EEG of freely-moving rats caused by three generation organophosphate treatment.- Developmental neurotoxicity of carbon monoxide.- Safety assessment of over the counter (OTC) products.- The safety assessment of over the counter (OTC) products.- OTC pharmaceuticals and genotoxicity testing: the paracetamol, anthraquinone, and griseofulvin cases.- Safety assessment of OTC products: doxylamine succinate.- Safety assessment of OTC products: a regulatory view.- Drug toxicity findings and no action taken.- Species specificity of organ toxicity.- Species specificity of organ toxicity.- Species specificity at the molecular level: the case of nitric oxide synthase.- Mechanisms underlying species-specificity in target organ specificity.- Species specificity of organ toxicity: behavioral differences.- Terrestrial ecotoxicity of chemical substances.- Development of OECD test guidelines and hazard assessment procedures for terrestrial effects.- Development of guidance for terrestrial effects assessment.- Application of quick and simple plant bioassays to assess the genotoxicity of environmental pollutants - Detection of potential health hazards of air, water and soil contaminants.- Comparison of susceptibility to chemicals (pesticides) of species used for human and environmental effect assessment.- Toxicological evaluation of pollutants in soil -concept of the AGU and assessment of tolerable concentrations for metals.- Immunodeflcient mouse systems.- The SCID (severe combined immnodeficiency) mouse - its biology and use in immunotoxicological research.- The SCID mouse as a tool to bridge the gap between animal and human responses.- The SCID mouse and its use in immunopharmacological and immunotoxicological investigations.- Stereochemical effects.- Chirality - from molecules to organisms.- Interactions between the in vitro metabolism of xenobiotics and fatty acids. The case of ibuprofen and other chiral profens.- Side effects and toxic reactions of chiral drugs: a clinical perspective.- Analysis of (S)-and (R)-propanolol in human plasma and urine by a specific immunoenzymtic assay versus HPLC.- Biological behavior of prestages of cancer cells.- Biological behavior of prestages of cancer cells: an introduction.- Preneoplastic lesions in kidney and carcinogenesis by non-genotoxic compounds.- Early cellular alterations in chemical liver carcinogenesis as assessed by immunohistochemical and molecular biological techniques.- Late Manuscripts.- The UK approach to the regulation and evaluation of novel foods produced by biotechnology.- Young Scientists Poster Award.- Molecular mimikry of CF3CO-lysine by lipoic acid I: the dehydrolipoamide acetyltransferase subunit of the human pyruvate dehydrogenase as autoantigen in halothane hepatitis.- Molecular mimikry of CF3CO-lysine by lipoic acid II: lipoic acid bearing proteins as autoantigen in halothane hepatitis.