Progress in the Chemistry of Organic Natural Products 115
(Sprache: Englisch)
This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found...
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This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
Inhaltsverzeichnis zu „Progress in the Chemistry of Organic Natural Products 115 “
Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis.- From Plant to Patient: Thapsigargin.- Antileishmanial Activity of Lignans and Neolignans.- Cryptolepine as a Lead to new Antiprotozoal Agents.- Biologically Active Constituents from Plants of the Genus Xanthium.
Bibliographische Angaben
- 2021, 1st ed. 2021, VII, 203 Seiten, 42 farbige Abbildungen, Masse: 17,2 x 24,2 cm, Gebunden, Englisch
- Herausgegeben: A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M Dirsch
- Verlag: Springer, Berlin
- ISBN-10: 3030648524
- ISBN-13: 9783030648527
Sprache:
Englisch
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