Pediatric Oncologic Pharmacy

Imatinib

4.18 Irinotecan

4.19 Lomustine

4.20 L-asparaginase

4.21 Methotrexate

4.22 Paclitaxel

4.23 Trans retinoic acid

4.24 Vinblastine

4.25 Vincristine

4.26 Vinorelbine



5. Physical-chemical compatibility of drugs used in chemotherapy for children

5.1 Brentuximab

5.2 Busulfan

5.3 Carboplatin

5.4 Carmustine

5.5 Cisplatin

5.6 Cyclophosphamide

5.7 Cytarabine

5.8 Dacarbazine

5.9 Daunorubicin

5.10 Docetaxel

5.11 Doxorubicin

5.12 Etoposide

5.13 Gentamicin

5.14 Idarubicin

5.15 Ifosfamide

5.16 Irinotecan

5.17 Lomustine

5.18 L-asparaginase

5.19 Methotrexate

5.20 Paclitaxel

5.21 Vinblastine

5.22 Vincristine

5.23 Vinorelbine



6. Drug Interactions involving chemotherapy for children

(This chapter will provide tables with very practical information of drug interactions, resumed mechanism of each interaction and, in case of undesirable interactions, alternatives to avoid them).



7. Prescription analysis

(This chapter will provide information about prescription analysis of protocols, doses, physical-chemical compatibilities, drug interactions, patients follow-up, laboratory tests and other pertinent subjects).



8. Handling pediatric chemotherapy

8.1 Intravenous 8.2 Intramuscular



8.3 Subcutaneous

8.4 For use in surgery



9. Handling pediatric intrathecal drugs

(This is a very important topic, given that intrathecal chemotherapy is largely used in pediatrics and it has many peculiarities).



10. Handling pediatric extemporaneous oral solutions with chemotherapy

(This is a very important topic aimed to pediatric oncology. Sometimes patients are neonates, infants or simply cannot swallow. This chapter will provide pharmacotechnical complete information to convert tablets into syrup, as shelf life, how to prepare each drug and other important subjects).



11. Administration of a pediatric oncology pharmacy: from the purchase of the drugs to the dispensation

(All administration subjects that pharmacists need to know to work in a Pediatric Oncology Pharmacy, as selective inventory control/ ABC curve, curve XYZ, selection of suppliers, lot tracking, traceability, receiving drugs, computerized system and reports).



12. Chemotherapy for pediatric stem cell transplantation

(Pharmacists even more handle chemotherapy for stem cell transplantation in children. Chemotherapy for stem cell transplantation varies a lot from that used for cancer and tumors treatment. This chapter will provide all information needed for a safety handling of these drugs for stem cell transplantation).



13. Biosafety for pharmacists and technical team in pediatric chemotherapy area

(This chapter will provide information about safety for pharmacists, appropriate equipment, necessary examinations, risks and other pertinent subjects).



14. Supportive therapy for pediatric patients receiving treatment with chemotherapy

14.1 Pediatric pain and the pharmacist

14.2 Pediatric nausea and vomiting and the pharmacist14.3 Pediatric infectious diseases during chemotherapy treatment and the pharmacist





15. Pediatric clinical pharmacy involving chemotherapy



16. Pediatric pharmaceutical care involving chemotherapy



17. Appendix

17.1 Body Surface Area

17.2 Tumor Lysis Syndrome



18. References