Pediatric Obesity

I. The Obesity Epidemic: A Global Perspective.- Global Dynamics in Childhood Obesity: Reflections on a Life of Work in the Field.- Childhood Malnutrition and the Origins of Obesity in the Developing World.- II. Hormonal and Metabolic Control of Appetite, Fat Deposition and Energy Expenditure.- The Neuroendocrine Control of Energy Balance.- GI Hormones and the Control of Food Intake.- The Microbiome and Control of Weight Gain.- III. Adipocyte Development and Function in Obesity and IR.- Control of White Adipose Tissue Development and Function in Obesity: Preclinical Models.- White Adipose Distribution and Function in Healthy and Obese Children.- Brown and Beige Fat: Development, Regulation and Function.- IV. The Genetics of Childhood Obesity.- Monogenic Obesity.- Syndromic Obesity.- Polygenic Obesity.- Racial Differences in Childhood Obesity: Pathogenesis and Complications.- V. Pre- and Perinatal Determinants of Childhood Obesity.- Maternal Determinants of Childhood Obesity: Weight Gain, Smoking, and Breastfeeding.- Intrauterine Growth Retardation.- Gestational Diabetes.- Endocrine Disruptors as Obesogens.- VI. The Role of Diet and Energy Expenditure in Obesity Pathogenesis.- Early Childhood Feeding Practices and Development of Childhood Obesity.- Macronutrients in the Development, Treatment and Prevention of Obesity: Two Views.- Carbohydrates and the Glycemic Index.- Caloric Intake, Caloric Density, and Fiber.- Energy Expenditure in Children: The Role of NEAT.- VII. Metabolic Complications of Childhood Obesity.- Childhood Obesity and the Regulation of Growth, Thyroid Function, Sexual Development and Calcium Homeostasis.- Metabolic Signatures in Childhood Obesity.- Pathogenesis of Insulin Resistance and Glucose Intolerance in Childhood Obesity.- Type 2 Diabetes in Children.- Pathogenesis and Management of Dyslipidemia in Obese Children.- Fatty Liver Disease.- Pathogenesis of Hypertension and

Michael S. Freemark, MD, Robert C. and Veronica Atkins Professor of Pediatrics, Chief, Division of Pediatric Endocrinology and Diabetes, Duke University School of Medicine, Durham, NC, USA

"There is no other book on pediatric obesity on the market that compares to this one. It covers all the basic sciences, social sciences, and clinical sciences that play a role in pediatric obesity. The most unique feature of this book is that at the end of each chapter, the author submits questions to the chapter authors. ... They give the book a great human touch." (Dyan Hes, Doody's Book Reviews, May, 2018)
"This is an analysis of the obesity epidemic in its social, cultural, economic, and political contexts. It highlights challenges and opportunities for pediatric obesity prevention and community action.  ... reviews of behavioural counselling, pharmacotherapy, and bariatric surgery provide practical guidance for the management of overweight children." (Journal of Consumer Policy, Vol. 42 (1), 2019)