mODa 9 - Advances in Model-Oriented Design and Analysis

Impact of Stratified Randomization in Clinical Trials.- The Non-Uniqueness of Some Designs for Discriminating Between Two Polynomial Models in One Variable.- Covariate Adjusted Designs for Combining Efficiency, Ethics and Randomness in Normal Response Trials.- Split-Plot and Robust Designs: Weighting and Optimization in the Multiple Response Case.- An Improvement in the Lack-of-Fit Optimality of the (Absolutely) Continuous Uniform Design in Respect of Exact Designs.- Optimal Allocation Proportion for a Two-Treatment Clinical Trial Having Correlated Binomial Responses.- Sample Size Determination for Multivariate Performance Analysis withComplex Designs.- Optimal Design for Compositional Data.- Dose Finding Experiments: Responses of Mixed Type.- Pharmacokinetic Studies Described by Stochastic DifferentialEquations: Optimal Design for Systems with Positive Trajectories.- On Testing Hypotheses in Response-Adaptive Designs Targeting the Best Treatment.- Towards Gaussian Process-based Optimization with Finite Time Horizon.- Optimal Designs for Linear Logistic Test Models.- A Class of Screening Designs Robust to Active Second-Order Effects.- D-Optimal Design for a Five-Parameter Logistic Model.- Sequential Barycentric Interpolation.- Some Considerations on the Fisher Information in Nonlinear Mixed Effects Models.- Designs with High Breakdown Point in Nonlinear Models.- A Note on the Relationship between Two Approaches to Optimal Design under Correlation.- The Role of the Nugget Term in the Gaussian Process Method.- A Bonferroni-Adjusted Trend Testing Method for Excess over Highest Single Agent.- Asymptotic Properties of Adaptive Penalized Optimal Designs over a Finite Space.- Filling and D-optimal Designs for the Correlated Generalized Exponential Model.- Designs for Dose Finding Studies on Safety and Efficacy.- A Radial Scanning Statistic for Selecting Space-filling Designs inComputer Experiments.- Optimal Designs for Two-Colour Microarray Experiments forEstimating

From the reviews:"The volume is a set of 30 articles strongly connected to the talks presented at the 9th International Workshop in Model-Oriented Design and Analysis. ... It offers the model-oriented approach to optimality of designs from theoretical point of view and gives real examples in many areas of applications. ... it presents the latest trends in optimal experimental designs research. The concepts in the book are presented in a very reader-friendly way, with many examples. ... highly recommended for anyone interested in design of experiments." (Katarzyna Filipiak, International Statistical Review, Vol. 79 (3), 2011)