IgE Antibodies: Generation and Function
(Sprache: Englisch)
This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation...
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Klappentext zu „IgE Antibodies: Generation and Function “
This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.Inhaltsverzeichnis zu „IgE Antibodies: Generation and Function “
Biology of IgE Production: IgE Cell Differentiation and the Memory of IgE Responses.- Molecular Mechanisms of IgE Class Switch Recombination.- Anti-IgE Therapy: Clinical Utility and Mechanistic Insights.- New Insights on the Signaling and Function of the High Affinity Receptor for IgE.- Helminth-Induced IgE and Protection Against Allergic Disorders.- IgE Immunotherapy Against Cancer.
Bibliographische Angaben
- 2015, 2015, IX, 152 Seiten, 16 farbige Abbildungen, Masse: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Juan J. Lafaille, Maria A. Curotto de Lafaille
- Verlag: Springer, Berlin
- ISBN-10: 3319137247
- ISBN-13: 9783319137247
- Erscheinungsdatum: 19.01.2015
Sprache:
Englisch
Pressezitat
"This book is a comprehensive, ideal resource for the allergologist, internist/general practitioner, oncologist, pediatrician, as well as the clinical laboratory-based allergologist and immunologist. Reading this book helps us review the basics, recognizing the role of the high affinity IgE receptor and all the surrounding characteristics that shape the allergic response. Most importantly, this book delves into the new applications of IgE-based therapeutics for helminth infections and cancer." (Paola de Baro-Alvarez, World Allergy Organization WAO, worldallergy.org, April, 2016)
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