Highlights in Bioorganic Chemistry
Methods and Apllications. Forew. by Ronald Breslow
(Sprache: Englisch)
This is a fascinating introduction to the topic. Spanning the spectrum of nucleic acid chemistry, carbohydrates, peptides, molecular recognition, biosynthesis and natural biosynthesis, right up to medical and biophysical chemistry, the book provides...
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Klappentext zu „Highlights in Bioorganic Chemistry “
This is a fascinating introduction to the topic. Spanning the spectrum of nucleic acid chemistry, carbohydrates, peptides, molecular recognition, biosynthesis and natural biosynthesis, right up to medical and biophysical chemistry, the book provides advanced students and those already working in the field with a balanced overview.In more than 30 contributions, a new generation of recognized scientists gives an account of the latest research in such areas as* Artificial receptors for the stabilization of ss-sheet structures* Carbohydrate recognition by artificial receptors* Combinatorial chemistry as a tool for the discovery of catalysts* The interaction of NO and peroxynitrite with hemoglobin and myoglobin* Inhibitors against human mast-cell-tryptase as a potential approach to conquering asthma* The selectivity of DNA replication.A readily accessible survey for everyone wishing to stay abreast of developments.With a Foreword by Ronald Breslow.
Inhaltsverzeichnis zu „Highlights in Bioorganic Chemistry “
STRUCTURE OF BIOMOLECULESb-amino acids in Nature: Biosynthesis and BiologyArtificial receptors for the stabilization of b-sheet structuresConformational equilibria of RNAConformational restriction of sphingolipidsStabilization of peptide-microstructures by coordniation of metal ionsSynthesis and application of proline and piccolic acid derivatives: tools for stabilization of peptide secondary structures.INTERMOLECULAR INTERACTIONS (BINDING)Artificial rotary motors at the molecular levelCarbohydrate recognition by artificial receptorsSynthetic approaches to study carbohydrate-lectin interactionsCyclopeptides as macrocyclic host molecules for charged guestsCombinatorial chemistry as a tool for the development of molecular receptors for small peptidesThe design of new binding motifs for c-terminal peptidesINTERACTION OF SMALL MOLECULES WITH BIOLOGICAL SYSTEMS (FUNCTION)Modulation of biochemical processes by synthetic hosts for substratesInteraction of NO and peroxynitrite with hemoglobin and myoglobinOxidative splitting of pyrimidine cyclobutane dimersInhibitors against human mast-cell-tryptase: a potential approach to attack asthma?Selectivity of DNA replicationAcridizinium salts and their photophysical interaction with DNADNA-detection in homogeneous solution
Autoren-Porträt
Carsten Schmuck is Professor of Organic Chemistry at the University of Würzburg. He studied chemistry and obtained his PhD at the Ruhr-University in Bochum. After a postdoctorate at Columbia University in New York, he carried out his Habilitation at the University of Cologne and joined the Unviersity of Würzburg as associate professor in 2002.Helma Wennemers is Professor of Organic Chemistry at the University of Basel. She studied chemistry at the Johann Wolfgand Goethe-University in Frankfurt and obtained her PhD at the Columbia University in New York. After a postdoctorate at Nagoya University in Japan she joined the University of Basel as assistant professor and was promoted to associate professor in 2003.
Bibliographische Angaben
- 2004, XXVIII, 572 Seiten, 219 Schwarz-Weiss-Abbildungen, 200 Abbildungen, Masse: 17,2 x 24,2 cm, Kartoniert (TB), Englisch
- Herausgegeben: Carsten Schmuck, Helma Wennemers
- Verlag: Wiley-VCH
- ISBN-10: 3527306560
- ISBN-13: 9783527306565
- Erscheinungsdatum: 14.01.2004
Sprache:
Englisch
Rezension zu „Highlights in Bioorganic Chemistry “
"Die Mehrzahl der Artikel sind lesenswert, leicht verständlich und bieten einen guten Überblick über das jeweilige Thema, ohne sich in Details zu verlieren. "Highlights in Bioorganic Chemistry" ist für jeden von Interesse, der sich für Bioorganik interessiert, denn das Buch zeigt die ganze Themenvielfalt auf."www.organische-chemie.ch3.3.04"Für Leser mit profunden Kenntnissen in organischer Chemie und Biochemie ist dieses Werk eine gut aufbereitetet Übersicht der aktuellen Entwicklung dieser Forschungsdisziplin und somit eine ideale Ergänzung zu Standard-Lehrbüchern. Viel Freude beim Entdecken spannender Ideen!" BioTec - Fachmagazin für Biotechnologie
Pressezitat
"...gives the average reader, on reading the contents, a general perspective of the scope of present-day bioorganic chemistry..."Chemistry and Industry, August 2004"The book consists of 35 chapters on various aspects of our chemical knowledge of various biological assemblies or of their model counterparts. The chapters have been written by various experts in the field, and I am naturally very stimulated by the state-of-the-art coverage that these colleagues have so nicely given to various aspects in a very professional manner. I have no doubt that the book will be helpful and interesting to both, beginners in the bioorganic research as well as to those who are practitioners in the field as a readily availabele reference book. ... This is a good, affordable reference book with plenty of citations to the review articles and original publications. I strongly recommend this as a reference or handbook to my both young and expert colleagues."Jyoti Chattopadhyaya, Uppsala University, Sweden, ChemBioChem. 12/2004"...should be found on the shelves of all chemistry libraries." Journal of the American Chemical Society, January 26, 2004
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