Frontiers in Computational and System Biology

Analysis of Combinatorial Gene Regulation with Thermodynamic ModelsChieh-Chun Chen and Sheng ZhongRNA Secondary Structure Prediction and Gene Regulation by Small RNAsYe DingSome Critical Data Quality Control Issues of OligoarraysWenjiang J. Fu, Ming Li, Yalu Wen and Likit PreeyanonStochastic-process Approach to Nonequilibrium Thermodynamics and Biological Signal TransductionHao GeGranger Causality: Theory and ApplicationsShuixia Guo, Christophe Ladroue and Jianfeng FengTranscription Factor Binding Site Identification by Phylogenetic FootprintingHaiyan Hu and Xiaoman LiLearning Network from High-dimensional Array Data Li Hsu, Jie Peng and Pei WangComputational Methods for Predicting Domain-Domain InteractionsHyunju Lee, Ting Chen and Fengzhu SunIrreversible Stochastic Processes, Coupled Diffusions and Systems BiochemistryPei-Zhe Shi and Hong QianProbability Modeling and Statistical Inference in Periodic Cancer ScreeningDongfeng Wu and Gary L. RosnerOn Construction of the Smallest One-sided Confidence Intervals and its Application in Identifying the Minimum Effective DoseWeizhen WangGroup Variable Selection Methods and Their Applications in Analysis of Genomic DataJun Xie and Lingmin ZengModeling Protein-Signaling Networks with Granger Causality TestWenqiang Yang and Qiang LuoDNA Copy Number Profiling in Normal and Tumor GenomesNancy R. ZhangSpatial Disease Surveillance: Methods and ApplicationsTonglin ZhangFrom QTL Mapping to eQTL AnalysisWei Zhang and Jun S LiuAn Evaluation of Gene Module Concepts in the Interpretation of Gene Expression DataXianghua Zhang and Hongyu ZhaoReadout of Spike Waves in a MicrocolumnXuejuan ZhangFalse Positive Control for Genome-wide ChIP-chip Tiling ArraysYu Zhang

From the reviews:"This mosaic of reviews and research precisely reflects the dynamic field of computational and systems biology. All of the major organizational levels of life are represented ... . Each chapter has a brief introduction to a biological subject, a review of the main mathematical and statistical models for that particular topic, and a description of the main applications and conclusions. There are an abundant number of references for each chapter. ... This compilation ... is likely to inspire generations of students, researchers, and readers." (Adrian Pasculescu, ACM Computing Reviews, January, 2011)