Extreme Hepatic Surgery and Other Strategies
Increasing Resectability in Colorectal Liver Metastases
(Sprache: Englisch)
This book describes the diagnoses; staging and management of patients with colorectal liver metastases initially considered unresectable and portrays the different strategies to increase resectability along with their tactics and tricks. Colorectal...
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This book describes the diagnoses; staging and management of patients with colorectal liver metastases initially considered unresectable and portrays the different strategies to increase resectability along with their tactics and tricks. Colorectal carcinoma is the third most commonly diagnosed cancer in the world and according to recent cancer statistics around 1.23 million patients are diagnosed each year. Of these patients, approximately 50% will develop liver metastases during the course of their disease and around 15-25% are found to have stage IV disease at diagnosis. Liver resection has been recognized as the treatment of choice for these patients, offering overall 5-year survival rates of up to 50-60% and the only hope for cure. However, at diagnosis only 10-20% of these patients are possibly amenable to surgical resection with curative intent. The possibility to achieve an R0 resection is many times limited by the amount and quality of the future liver remnant (FLR), being posthepatectomy liver failure (PHLF) the most feared and severe complication after major liver resections. With the years, diverse strategies have been developed with the intention to increase resectability by increasing the future liver remnant and/or reducing tumor size, e.g. ALPPS. Along with these techniques, associated surgeries are developed including multivisceral resections, which broadens even more the resectability for patients.
Inhaltsverzeichnis zu „Extreme Hepatic Surgery and Other Strategies “
I- Introduction1- Introduction
2- Understanding tumor biology in advanced tumors
3- Liver Surgical Anatomy
II- Global patient evaluation and oncological assessment
4- resectability assessment with diagnostic imaging
5- liver function evaluation
6- Risk assessment for extreme liver surgery
7- choosing the best strategy
III- Non-operative multimodal therapies
8- Conversion and neoadjuvant therapies. Pros and cons
9- Portal embolization
10- Intraarterial chemotherapy
11- Radioembolization
IV- Surgical strategies
12- Anesthetics management
13- Intraoperative evaluation of resectability
14- Vascular control in major Hepatic resections
15- Synchronous disease: classic, simultaneous or reverse approach
16- Two-stage liver surgery
17- Two-stage liver surgery with portal occlusion
18- ALPPS
19- Combined liver resection and local therapies
20- Combined Vascular resections
21- Ex-vivo liver surgery
22- Liver transplant
V- Management of concomitant extrahepatic disease
23- Pulmonary metastases
24- Nodal involvement
25- Peritoneal disease
26- Adjacent organs invasion. Multivisceral resections
VI- Postoperative complications and their management
VII- Palliative care
Autoren-Porträt
Eduardo de Santibañes MD, PhD, Full Professor of Surgery at University of Buenos Aires (2005-2013) and Full Professor and Head of the Surgery Department (Hospital Italiano, 2008-2012). Chairman of the General Surgery Service since 2005, one of the most active Surgical services of Latin America, having performed over 7,400 procedures in 2013. Chairman of the Liver Transplant Unit of the Hospital Italiano since 1985. Former Chairman of the World Congress of the Hepato Pancreato Biliary Association; Argentine Academy of Surgery, Argentine Association of Surgery, Argentine Liver Transplant Society and the Argentine Chapter of the International Hepato Pancreato Biliary Association. Honorary Member of the American Surgical Association, German Surgical Society, European Surgical Association, among others. Victoria Ardiles MD, PhD, General Surgeon (University of Buenos Aires), Laparoscopic Surgeon (Argentine Association of Surgery) and HPB surgeon (Hospital Italiano de Buenos Aires). Professorof Surgery at University of Buenos Aires and Associated Professor and Coordinator of the Surgery Department of the University School of Medicine, Hospital Italiano. Associated staff of the General Surgery Service, member of the Liver Transplant Unit and General coordinator of the Department of Surgery, Hospital Italiano de Buenos Aires. Martin de Santibañes Surgeon at Liver Transplantation and HPB Unit, Hospital Italiano de Buenos Aires. Assistant Professor Hospital Italiano de Buenos Aires School of Medicine. General Surgery Residency Co-Director, Hospital Italiano de Buenos Aires. Fernando Alvarez MD. Fellowship of HPB Surgery and Liver Transplant at the Italian Hospital of Buenos Aires (2013-2014). Received the "Eduardo F. Beláustegui Award" from the Argentine Surgical Association (2008) and the "Annual Award" from the Argentine Academy of Surgery (2014). Virginia Cano Busnelli MD with Residency training at Italian Hospital of Buenos Aires.
Bibliographische Angaben
- 2017, 1st ed. 2017, XIX, 383 Seiten, 137 farbige Abbildungen, Masse: 18,4 x 26,4 cm, Gebunden, Englisch
- Herausgegeben: Eduardo de Santibañes, Martin de Santibañes, Victoria Ardiles, Fernando Alvarez, Virginia Cano Busnelli
- Verlag: Springer, Berlin
- ISBN-10: 3319138952
- ISBN-13: 9783319138954
- Erscheinungsdatum: 14.08.2017
Sprache:
Englisch
Pressezitat
"This book is devoted to difficult problems in hepatic resection for colorectal metastatic disease. It is an attempt to bring together, in a series of chapters, a lot of information about the current status of liver resection (including transplantation) and apply it to this common problem. ... It is most likely to be of use to specialists, who may find in its pages additional information or guidance on specific complex problems and techniques." (Carol Scott-Conner, Doody's Book Reviews, October, 2017)Kommentar zu "Extreme Hepatic Surgery and Other Strategies"
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