Cancer Epigenetics

Part-1. Background.- Chapter 1. An Overview of Epigenetics Modifications in Normal and Cancer Cell.- Chapter 2. Epigenetic Enzymes and Mutation of Epigenetic Enzymes.- Chapter 3. Introduction to Cancer Epigenetics.- Part II. Cancer Specific Epigenetic Alterations.- Chapter 4. Epigenetics in the Diagnosis, Prognosis and Therapy of Cancer.- Chapter 5. The Clinical Studies and Epi-Drugs In Various Cancer Types.- Chapter 6. Epigenetic Regulation in Breast Cancer Tumor Microenvironment.- Chapter 7. The Epigenetics Of Brain Tumors: Fundamental Aspects Of Epigenetics In Glioma.- Chapter 8. Epigenetic Alterations in Pancreatic Cancer.- Chapter 9. Current Preclinical Applications of Pharmaco-Epigenetics in Cardiovascular Diseases.- Chapter 10. Epigenetic Alterations in Colorectal  Cancer.- Chapter 11. Epigenetic Alterations in Hematopoietic Disorders.

Rasime Kalkan is  a Professor of Medical Genetics.  She completed her PhD in the Department of Medical Genetics at the Eskisehir Osmangazi University in Turkey and worked as a member of the Department of Medical Genetics at the Near East University between November 2011 and June 2022. In 2020 she was appointed Chair of the Department of Molecular Biology and Genetics of the Arts and Sciences Faculty at Near East University. She was the founding Dean of the Faculty of Medicine of Cyprus Health and Social Sciences University in Cyprus between July 2022 and August 2023. She was Vice-Rector at the Cyprus Health and Social Sciences University (CHSSU) in Cyprus between July 2022 and August 2023.

Professor Kalkan is a member of Turkish Medical Genetics Association (since 2006) and a member of the board of directors of the Turkish Cypriot Association of Human Genetics (since 2022).



During her PhD, her research focused on genetic and epigeneticalterations in brain tumors, especially in glioblastoma. She has published numerous articles in peer-reviewed journals and authored several chapters for various national and international books. Furthermore, she was involved in many research projects as project coordinator and assistant investigator. Her current research is focused on the identification of epigenetic and genetic alterations in cancer, obesity and post-menopausal term.