Bio/CMOS Interfaces and Co-Design

Introduction.- Chemistry of Conductive Solutions.- Biochemistry of Targets and Probes.- Target/Probe interactions.- Surface Immobilization of Probes.- Nano Technology to prevent Electron Transfer.- Bio/CMOS interface for Label-free Capacitance Sensing.- nanotechnology to enhance electron transfer.- Bio/CMOS interface in Constant Bias.-Bio/CMOS interface in Voltage Scan.- Appendix 1 - Basic Chemistry.- Appendix 2 - Basic Configurations of Operational Amplifiers.- Appendix 3 - The Fourier Theorem.- Appendix 4 - The Fourier and Laplace Transforms.

Sandro Carrara is an IEEE Fellow for his outstanding record of accomplishments in the field of design of nanoscale biological CMOS sensors. He is also the recipient of the IEEE Sensors Council Technical Achievement Award in 2016 for his leadership in the emerging area of co-design in Bio/Nano/CMOS interfaces. He is a Professor at the EPFL, the École Polytechnique Federal de Lausanne (Switzerland). He is former professor of optical and electrical biosensors at the Department of Electrical Engineering and Biophysics (DIBE) of the University of Genoa (Italy) and former professor of nanobiotechnology at the University of Bologna (Italy). He holds a PhD in Biochemistry and Biophysics from University of Padua (Italy), a Master degree in Physics from University of Genoa (Italy), and a diploma in Electronics from National Institute of Technology in Albenga (Italy). His scientific interests are on electrical phenomena of nano-bio-structured films, and include CMOS design of biochips based on proteins and DNA. Along his carrier, he published 8 books with prestigious publishers, including this book with Springer about Bio/CMOS interfaces and a Handbook of Bioelectronics with Cambridge University Press. He also published more than 350 scientific papers and is author of 17 patents. He is now Editor-in-Chief of the IEEE Sensors Journal (one of the largest among more than 220 IEEE publications); he is also founder and Editor-in-Chief of the journal BioNanoScience by Springer, and Associate Editor of IEEE Transactions on Biomedical Circuits and Systems. He is an executive member of the IEEE Sensors Council and was a member of the Board of Governors (BoG) of the IEEE Circuits And Systems Society (CASS). He has been appointed as IEEE Sensors Council Distinguished Lecturer for the years 2017-2019, and CASS Distinguished Lecturer for the years 2013-2014. His work received many international recognitions: several Top-25 Hottest-Articles (2004, 2005, 2008, 2009, and two times in