Spatially Fractionated, Microbeam and FLASH Radiation Therapy (ePub)
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This textbook is a comprehensive review of the physics of heterogeneous radiation and is linked, through a multidisciplinary approach, to clinical applications and biological considerations of heterogenous radiation. Fundamental principles of Spatially Fractionated Radiation Therapy (SFRT), techniques and technologies, dosimetric properties of SFRT, planning methods, documentation, standardized reporting metrics and clinical practice recommendations are comprehensively reviewed. The current status and results of clinical patient studies are presented, which have the potential to advance the management of bulky and advanced tumors. Potential biological underpinnings are reviewed that may challenge the current radiobiological understanding of radiation response and radiation therapy design parameters. Such multidisciplinary understanding is a critical foundation as the field of heterogeneous radiation rapidly advances in technological development and clinical investigation.
Key Features
- GRID collimator- and MLC-based GRID therapy
- 3D Lattice radiation therapy
- FLASH radiation therapy
- Minibeam and microbeam therapy
- Proton beam GRID therapy
- SFRT dose prescription
- GRID and Lattice therapy plan evaluation and documentation
- Clinical applications of SFRT and patient outcomes
- Monte Carlo simulation techniques of SFRT
- Practical applications and procedures (where appropriate)
- Biological correlations and potential biological underpinnings
- Immune phenomena in SFRT
Nina A. Mayr, MD is Professor and Senior Academic Advisor in the Office of Health Sciences at Michigan State University. She previously served as chair of Department of Radiation Oncology and endowed professor in the University of Washington School of Medicine. Her specialities include advanced radiation therapy modalities; imaging and image-guided radiation; and imaging predictors of cancer treatment outcomes, for which she received two R01 grant awards; women cancers; lung cancer and neuro radiation oncology. She serves as chair of the Radiosurgery Society GRID/Lattice, Microbeam and Flash Radiation Therapy Clinical Working Group. She has been awarded the elected Fellow of the American Association of the Advancement of Science (AAAS), Fellow of ASTRO, and the American Board of Radiology Lifetime Service Award for her contributions to research and education. She has published over 200 journal articles.
- 2023, 250 Seiten, Englisch
- Herausgegeben: Hualin Zhang, Nina Mayr
- Verlag: Institute of Physics Publishing
- ISBN-10: 0750340460
- ISBN-13: 9780750340465
- Erscheinungsdatum: 29.06.2023
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- Dateiformat: ePub
- Grösse: 14 MB
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