Replicating Vaccines / Birkhäuser Advances in Infectious Diseases (PDF)
A New Generation
(Sprache: Englisch)
Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines. Historically, live vaccines have been either directly...
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Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines. Historically, live vaccines have been either directly derived from a natural source or attenuated by empirical approaches using serial passages and host cell adaptation. Currently, we are witnessing a quantum leap in our technological capabilities to specifically modify the genetic make-up of viruses and bacteria, making it possible to generate improved live vaccines and to develop completely new types of replicating vaccines, such as vectored vaccines, single-round infectious vaccines and replicon vaccines.
This book highlights some of the most exciting recent developments towards a new generation of replicating vaccines.
This book highlights some of the most exciting recent developments towards a new generation of replicating vaccines.
Bibliographische Angaben
- Autor: Rino Rappuoli
- 2010, 2011, 447 Seiten, Englisch
- Herausgegeben: Philip R. Dormitzer, Christian W. Mandl, Rino Rappuoli
- Verlag: Springer-Verlag GmbH
- ISBN-10: 3034602774
- ISBN-13: 9783034602778
- Erscheinungsdatum: 02.11.2010
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- Dateiformat: PDF
- Grösse: 6.14 MB
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Sprache:
Englisch
Pressezitat
From the reviews:“This book introduces the current thinking on rational attenuation and this important theme runs through the book, tying the chapters together very nicely. … Given the renaissance in vaccinology this is a timely volume which … makes judicious use of selected examples to highlight key aspects of this burgeoning field. This book is both a useful primer for students and a thought-provoking read for researchers in this field.” (Paul Duprex, Microbiology Today, November, 2011)
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