Oral Delivery of Therapeutic Peptides and Proteins (ePub)
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Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport.
Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource.
- Demonstrates how proteins and peptides transport throughout the gastrointestinal tract and how to evaluate their biological fate when encapsulated into certain delivery systems
- Examines developing technologies to improve future oral bioavailability
- Includes the in vitro and preclinical techniques needed for development
- 2022, 316 Seiten, Englisch
- Herausgegeben: Puneet Tyagi, Anand Subramony
- Verlag: Elsevier Science & Techn.
- ISBN-10: 0128210605
- ISBN-13: 9780128210604
- Erscheinungsdatum: 18.08.2022
Abhängig von Bildschirmgrösse und eingestellter Schriftgrösse kann die Seitenzahl auf Ihrem Lesegerät variieren.
- Dateiformat: ePub
- Grösse: 9.94 MB
- Mit Kopierschutz
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