Mass Spectrometry for Drug Discovery and Drug Development / Wiley-Interscience Series on Mass Spectrometry (ePub)

Facilitates the discovery and development of new, effective
therapeutics

With coverage of the latest mass spectrometry technology, this
book explains how mass spectrometry can be used to enhance almost
all phases of drug discovery and drug development, including new
and emerging applications. The book's fifteen chapters have been
written by leading pharmaceutical and analytical scientists. Their
contributions are based on a thorough review of the current
literature as well as their own experience developing new mass
spectrometry techniques to improve the ability to discover and
develop new and effective therapeutics.

Mass Spectrometry for Drug Discovery and Drug Development
begins with an overview of the types of mass spectrometers that
facilitate drug discovery and development. Next it covers:

* HPLC-high-resolution mass spectrometry for quantitative
assays

* Mass spectrometry for siRNA

* Quantitative analysis of peptides

* Mass spectrometry analysis of biological drugs

* Applications that support medicinal chemistry
investigations

* Mass spectrometry imaging and profiling

Throughout the book, detailed examples underscore the growing
role of mass spectrometry throughout the drug discovery and
development process. In addition, images of mass spectra are
provided to explain how results are interpreted. Extensive
references at the end of each chapter guide readers to the primary
literature in the field.

Mass Spectrometry for Drug Discovery and Drug Development
is recommended for readers in pharmaceutics, including medicinal
chemists, analytical chemists, and drug metabolism scientists. All
readers will discover how mass spectrometry can streamline and
advance new drug discovery and development efforts.