Islet Transplantation and Beta Cell Replacement Therapy (PDF)

A. M. JAMES SHAPIRO is Professor of Surgery, Division of General Surgery, University of Alberta, Canada, and Director of Clinical Islet Transplant Program, Staff Surgeon, and Director of the Juvenile Diabetes Foundation Clinical Center for Islet Transplantation, University of Alberta Hospital, Canada. Dr. Shapiro received his M.B.B.S. from the University of Newcastle on Tyne, England, and his Ph.D. in Experimental Surgery, University of Alberta. Dr. Shapiro currently investigates islet transplantation for the treatment of type 1 diabetes and the immunobiology and tolerance induction for islet cell transplantation, and currently has written over 150 peer reviewed articles and over 15 books and chapters in the field of diabetes.

JAMES A. M. SHAW is a Senior Lecturer in Diabetes at the University of Newcastle within the Institute of Cellular Medicine, Institute of Cell and Molecular Biosciences and the North East Stem Cell Institute. He is a consultant physician in the Newcastle upon Tyne Acute Hospitals Foundation Trust and the Newcastle Primary Care Trust. Dr Shaw received his BSc from St Andrews University, Scotland; MB ChB from the University of Manchester, England; and PhD from the University of Aberdeen, Scotland. He held a Medical Research Council Training Fellowship and GlaxoSmithKline Senior Fellowship. He is a Fellow of the Royal College of Physicians of Edinburgh. In addition to his clinical interests in insulin pump therapy, pancreas and islet transplantation, his research group are exploring gene therapy for diabetes and beta cell replacement including stem cell approaches.