High-Density Lipoproteins (ePub)
Structure, Metabolism, Function and Therapeutics
(Sprache: Englisch)
A complete guide to the role of high-density lipoproteins (HDL)
in new and emerging therapies
With high-density lipoproteins (HDL) playing an increasing role
in cardiovascular disease prevention, there is a growing need for
an in-depth look at HDL and...
in new and emerging therapies
With high-density lipoproteins (HDL) playing an increasing role
in cardiovascular disease prevention, there is a growing need for
an in-depth look at HDL and...
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A complete guide to the role of high-density lipoproteins (HDL)
in new and emerging therapies
With high-density lipoproteins (HDL) playing an increasing role
in cardiovascular disease prevention, there is a growing need for
an in-depth look at HDL and its clinical value. This book
summarizes the current state of knowledge in the field, providing
for the first time a comprehensive, systematic, stylistically
coherent, and up-to-date review of the composition, structure,
heterogeneity, metabolism, epidemiology, genetics, and function of
HDL.
Divided into three main parts, High-Density Lipoproteins first
examines normal HDL particles, then describes defective HDL, and
finally addresses the therapeutic normalization of subnormal levels
and defective biological activities of this lipoprotein class. The
book highlights the functional properties of HDL, which are
relevant to the pathophysiology of atherosclerosis and thrombosis,
and discusses the compositional and metabolic heterogeneity of HDL
particles.
Readers will come away with a clear understanding of the role of
HDL in biological processes, the potential value of functional HDL
as a therapeutic target, and how current and emerging therapies are
poised to influence the treatment of heart disease in the
future.
in new and emerging therapies
With high-density lipoproteins (HDL) playing an increasing role
in cardiovascular disease prevention, there is a growing need for
an in-depth look at HDL and its clinical value. This book
summarizes the current state of knowledge in the field, providing
for the first time a comprehensive, systematic, stylistically
coherent, and up-to-date review of the composition, structure,
heterogeneity, metabolism, epidemiology, genetics, and function of
HDL.
Divided into three main parts, High-Density Lipoproteins first
examines normal HDL particles, then describes defective HDL, and
finally addresses the therapeutic normalization of subnormal levels
and defective biological activities of this lipoprotein class. The
book highlights the functional properties of HDL, which are
relevant to the pathophysiology of atherosclerosis and thrombosis,
and discusses the compositional and metabolic heterogeneity of HDL
particles.
Readers will come away with a clear understanding of the role of
HDL in biological processes, the potential value of functional HDL
as a therapeutic target, and how current and emerging therapies are
poised to influence the treatment of heart disease in the
future.
Inhaltsverzeichnis zu „High-Density Lipoproteins (ePub)“
Dedication. Contents. Abbreviations. Preface. Acknowledgements. Section 1. Normal functional HDL. Chapter 1.1 Composition. Chapter 1.2 Heterogeneity. Chapter 1.3 Structure. 1.4 Metabolism. 1.5 Epidemiology of HDL-C. Chapter 1.6 Genetics. Chapter 1.7 Biological activities. Section 2. Functionally defective HDL. Chapter 2.1 Altered composition. Chapter 2.2 Abnormal metabolism. Chapter 2.3 Impaired biological activities. Section 3. Therapeutic normalization of subnormal levels and defective biological activities of HDL. Chapter 3.1 Enhancement of HDL formation and normalization of intravascular HDL remodeling. Chapter 3.2 Combination therapies. Chapter 3.3 Other pharmacological approaches. Chapter 3.4 Lifestyle modifications. Conclusions and perspectives.
Autoren-Porträt von Anatol Kontush, M. John Chapman
Anatol Kontush, BSc (Hons), PhD, is Research Director at theDyslipidemia and Atherosclerosis Research Unit of the National
Institute of Health and Medical Research (INSERM) at the
Pitié-Salpêtrière Hospital, Paris, France. An
award-winning scientist, Dr. Kontush has authored more than 100
original papers and book chapters.
M. John Chapman, BSc, PhD, DSc, FESC, is President of the
European Atherosclerosis Society and Director of the Dyslipidemia
and Atherosclerosis Research Unit of the National Institute of
Health and Medical Research (INSERM) at the
Pitié-Salpêtrière Hospital in Paris, France,
affiliated with the medical faculty of the Pierre and Marie Curie
University, Paris. He has authored more than 400 articles and book
chapters.
Bibliographische Angaben
- Autoren: Anatol Kontush , M. John Chapman
- 2011, 1. Auflage, 648 Seiten, Englisch
- Verlag: John Wiley & Sons
- ISBN-10: 1118158660
- ISBN-13: 9781118158661
- Erscheinungsdatum: 29.11.2011
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eBook Informationen
- Dateiformat: ePub
- Grösse: 9.09 MB
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Sprache:
Englisch
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