Guidelines and Screening Methods of Pharmacology (ePub)

Drug Discovery is the process by which new molecules are discovered and now a days everybody is becoming aware of its level of importance especially in this era of COVID 19, which creates a possible anticipation of an increment in the demand for books related to screening methods of pharmacology. Pharmacological screening of drugs is a sequential testing of new chemical entities or extracts from biological material in isolated organs followed by test in whole experimental animals. Screening Methods in Pharmacology focuses on the methods for screening of moieties for pharmacological activities and discussions for organization of screening programs. This book envelops a descriptive approach detailed about CPCSEA, OECD and ICH guidelines that must be followed during screening of new drug moieties. It also provides a brief idea about bioassay and research methodology along with various experimental animal screening models for different diseases. This book shall serve as a reference guide for students of Pharmacy and life sciences graduates.

Salient Features:

1. Beneficial for Pharmacy and life science graduates and research scholars.

2. Provides various experimental animal screening models for different diseases.

3. Gives special guidelines for animal use during experimental protocols.

4. Provides brief description about Bioassay

Contents:



1. Regulations for Laboratory Animals Care and Ethical Requirements

2. Pharmacological Techniques for Evaluation of Drugs on Different Systems

3. Bioassay

4. Evaluation of Drugs acting on Autonomic Nervous System

5. Evaluation of Drugs Acting on Central Nervous System

6. Evaluation of Drugs Acting on Respiratory System

7. Evaluation of Drugs Acting on Eye

8. Evaluation of Drugs Acting on Cardiovascular System

9. Evaluation of Drugs Acting on Endocrine System

10. Evaluation of Drug Acting on Kidney

11. Miscellaneous

12. Transgenic Animals and other Genetically Modified Animal Models

13. Drug Toxicity and Safety Evaluation

14. Alternatives to Animal Screening Procedures

15. New Approaches in Drug Discovery

16. Research Methodology

About the Authors:

Surendra H. Bodakhe (M.Pharm., Ph.D, FIC) is currently working as Associate Professor of Pharmacology, at SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (Chhattisgarh). He has about 24 years of multifaceted experience in academics and research. He has to his name more than 60 publications in different journals of National and International repute, 4 books and one US patent. He is life member of APTI and Pharmacological Society of India. About 50 M. Pharmacy students and 6 Ph.D. research scholars have benefited from his guidance. He worked as co-coordinator in UGC-SAP project worth 90 lakhs. He has completed major and minor projects from various funding agencies like AYUSH (Govt of India), CGCOST.