Essentials of Apoptosis (PDF)

Recent apoptosis research has revealed the process' complex molecular and biochemical mechanisms, even as it has also complicated its study, particularly when trying to generalize findings from multiple laboratories or applying methods used in one context to another system. In Essentials of Apoptosis: A Guide for Basic and Clinical Research, experienced investigators have systematically compiled a comprehensive but concise summary of essential, up-to-date information about apoptosis. The authors present the concepts, the molecular architecture, the biochemical pathways, and the pathophysiological significance of apoptosis. In addition, standard biochemical and cell biologic approaches to apoptosis research are described as a guideline for bench work, with clinical applications detailed for immune disorders, cancer, ischemia/reperfusion injury, and neuronal degeneration. Coverage extends to a broad range of biological systems, from bacteria, plants, worms, and fruit flies to mammals.

Comprehensive and highly instructive, Essentials of Apoptosis: A Guide for Basic and Clinical Research systematically presents the core concepts of apoptosis, providing both a user-friendly introduction for those new to the field and an up-to-date reference for established researchers seeking an integrated understanding of apoptosis and new avenues for its productive investigation.