Computational Methods for Mass Spectrometry Proteomics (PDF)

Proteomics is the study of the subsets of proteins present in
different parts of an organism and how they change with time and
varying conditions. Mass spectrometry is the leading technology
used in proteomics, and the field relies heavily on bioinformatics
to process and analyze the acquired data. Since recent
years have seen tremendous developments in instrumentation and
proteomics-related bioinformatics, there is clearly a need for a
solid introduction to the crossroads where proteomics and
bioinformatics meet.

Computational Methods for Mass
Spectrometry Proteomics describes the different
instruments and methodologies used in proteomics in a unified
manner. The authors put an emphasis on the computational methods
for the different phases of a proteomics analysis, but the
underlying principles in protein chemistry and instrument
technology are also described. The book is illustrated by a number
of figures and examples, and contains exercises for the reader.
Written in an accessible yet rigorous style, it is a valuable
reference for both informaticians and biologists.

Computational Methods for Mass Spectrometry
Proteomics is suited for advanced undergraduate and graduate
students of bioinformatics and molecular biology with an interest
in proteomics. It also provides a good introduction and reference
source for researchers new to proteomics, and for people who come
into more peripheral contact with the field.