Chemometric Methods in Capillary Electrophoresis (PDF)

PREFACE. ACKNOWLEDGMENTS. EDITOR BIOGRAPHIES. CONTRIBUTORS. KEY ACRONYMS. I EXPERIMENTAL DESIGN AND OPTIMIZATION CONSIDERATIONS. 1 INTRODUCTION (Grady Hanrahan and Frank A. Gomez). 2 EXPERIMENTAL DESIGN IN METHOD OPTIMIZATION AND ROBUSTNESS TESTING (Bieke Dejaegher, Alexandra Durand, and Yvan Vander Heyden). 3 CHEMOMETRICAL EXPERIMENTAL DESIGN-BASED OPTIMIZATION STUDIES IN CAPILLARY ELECTROPHORESIS APPLICATIONS (Ruthy Montes, Toni Ann Riveros, Froseen Dahdouh, Grady Hanrahan, and Frank A. Gomez). 4 APPLICATION OF CHEMOMETRIC METHODS IN DRUG PURITY DETERMINATION BY CAPILLARY ELECTROPHORESIS (Gerhard K.E. Scriba). 5 OPTIMIZATION OF MICELLAR ELECTROKINETIC CHROMATOGRAPHY SEPARATION CONDITIONS BY CHEMOMETRIC METHODS (Jessica L. Felhofer and Carlos D. Garcia). 6 CHEMOMETRIC METHODS FOR THE OPTIMIZATION OF CE AND CE-MS IN PHARMACEUTICAL, ENVIRONMENTAL, AND FOOD ANALYSIS (Javier Hernández-Borges, Miguel Ángel Rodríguez-Delgado, and Alejandro Cifuentes). 7 OPTIMIZATION OF THE SEPARATION OF AMINO ACIDS BY CAPILLARY ELECTROPHORESIS USING ARTIFICIAL NEURAL NETWORKS (Amanda Van Gramberg, Alison Beavis Lucas Blanes, and Philip Doble). II EXPLORATORY DATA ANALYSIS, PREDICTION, AND CLASSIFICATION. 8 DEVELOPMENT OF CAPILLARY ELECTROPHORESIS FINGERPRINTS AND MULTIVARIATE STATISTICS FOR THE DIFFERENTIATION OF OPIUM AND POPPY STRAW SAMPLES (Raymond G. Reid, Susanne P. Boyle, Ann S. Low, and David G. Durham). 9 MULTIVARIATE CURVE RESOLUTION BASED ON ALTERNATING LEAST SQUARES IN CAPILLARY ELECTROPHORESIS (Javier Saurina). 10 APPLICATION OF CHEMOMETRICS IN CAPILLARY ELECTROPHORESIS ANALYSIS OF HERBAL MEDICINES (Shao-Ping Li, Xiao-Jia Chen, and Feng-Qing Yang). 11 CLINICAL PATTERN RECOGNITION ANALYSIS APPLYING ARTIFICIAL NEURAL NETWORKS BASED ON PRINCIPAL COMPONENT ANALYSIS INPUT SELECTION (Yaxiong Zhang and Hua Li). 12 CHEMOMETRIC METHODS APPLIED TO GENETIC ANALYSES BY CAPILLARY ELECTROPHORESIS AND ELECTROPHORESIS MICROCHIP TECHNOLOGIES (Maribel Elizabeth Funes-Huacca, Juliana Vieira

Grady Hanrahan, PhD, received his doctorate in environmental
analytical chemistry from the University of Plymouth, England. Dr.
Hanrahan is currently the John Stauffer Endowed Professor of
Analytical Chemistry at California Lutheran University with
research interests in the use of modern chemometric methods in the
design and development of environmental and bioanalytical
instrumentation. He is also exploring the use of neural and
evolutionary computational techniques for solving complex chemical
problems.

Frank A. Gomez, PhD, received his BS in chemistry from
California State University, Los Angeles (CSULA), and his PhD in
chemistry from UCLA, where he was a NIH Predoctoral Fellow. From
1991-1994, he was a Damon Runyon-Walter Winchell Cancer
Research Fund Postdoctoral Fellow in the department of chemistry at
Harvard University. He is a professor of chemistry at CSULA and is
a visiting associate at Caltech in the Applied Physics
department.

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