Brain Edema (ePub)
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Brain Edema: From Molecular Mechanisms to Clinical Practice brings together the most widely recognized experts in experimental and clinical brain edema research to review the current knowledge gathered on the molecular and cellular pathophysiology and clinical management of brain edema. This timely book also discusses future directions of research and treatment.
Brain edema is an integral and acutely life-threatening part of the pathophysiology of multiple cerebral and non-cerebral disorders, including traumatic brain injury, cerebral ischemia, brain tumors, cardiac arrest, altitude sickness and liver failure. Affecting millions worldwide, research over the past few years has shown that a plethora of complex molecular and cellular mechanisms contribute to this pathological accumulation of water in the brain parenchyma.
In parallel, the development of new neuroimaging tools has provided a new way to examine how edema develops longitudinally and in real time, both in pre-clinical models and in patients. Despite intense research over the past few decades, therapeutic options are still limited and sometimes not effective.
- Presents a comprehensive understanding of the molecular mechanisms involved in edema formation and resolution
- Discusses the specific role of edema development in several pathologies, including traumatic brain injury, stroke, brain tumors, cardiac arrest, and liver failure
- Proposes a new classification of edema based on molecular processes
- Discusses clinical management of new clinical trials coming from pre-clinical studies
- Addresses the possible link between edema formation, other molecular and cellular processes, including inflammation and neuroinflammation
Dr. Plesnila studied medicine in Regensburg and Munich, Germany, and spend the first few years of his scientific carrier working on the molecular mechanisms of astrocytic cell swelling in the laboratory of Axel Baethmann at the Institute for Surgical Research, Munich, Germany. After a post-doctoral fellowship at Harvard Medical School, he expanded his research interests to traumatic brain injury and cerebral ischemia in vivo. After research professorships at the Department of Neurosurgery in the University of Munich and at the Royal College of Surgeons in Ireland (RCSI), Dr. Plesnila’s laboratory
- 2017, 554 Seiten, Englisch
- Herausgegeben: Jerome Badaut, Nikolaus Plesnila
- Verlag: Elsevier Science & Techn.
- ISBN-10: 0128031972
- ISBN-13: 9780128031971
- Erscheinungsdatum: 29.09.2017
Abhängig von Bildschirmgrösse und eingestellter Schriftgrösse kann die Seitenzahl auf Ihrem Lesegerät variieren.
- Dateiformat: ePub
- Grösse: 10 MB
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