Wilson Disease

1. History of Wilson disease: a personal account
J M. Walshe
2. Epidemiology and introduction to the clinical presentation of Wilson disease
Christine Lo and Oliver Bandmann
3. The Genetics of Wilson disease
Sihoun Hahn
4. Genetic and environmental modifiers of Wilson disease
Valentina Medici and Karl Heinz Weiss
5. Pathogenesis of Wilson disease
Petr Dusek, Radan Bruha and Ivo Florin Scheiber
6. Animal models of Wilson disease
Dominik Huster and Valentina Medici
7. Wilson disease - liver pathology
Maciej Pronicki
8. Wilson disease - brain pathology
France Woimant, Aurelia Poujois and Jacqueline Mikol
9. Hepatic features of Wilson disease
Michael L. Schilsky, Aftab Ala and Salih Boga
10. Wilson disease: neurologic features
Anna Czlonkowska, Tomasz Litwin and Grzegorz Chabik
11. Cognitive and psychiatric symptoms in Wilson disease
Paula C. Zimbrean and Joanna Seniow
12. Wilson's disease in children
Eve A. Roberts and Piotr Socha
13. Other organ involvement and clinical aspects of Wilson disease
Karolina Dziezyc, Tomasz Litwin and Anna Czlonkowska
14. Diagnosis of Wilson disease
Peter Ferenci
15. Wilson disease - currently used anti-copper therapy
Anna Czlonkowska and Tomasz Litwin
16. Liver transplantation for Wilson disease
Michael L. Schilsky
17. Wilson disease - symptomatic liver therapy
Wolfgang Stremmel and Karl Heinz Weiss
18. Symptomatic treatment of neurologic symptoms in Wilson disease.
Tomasz Litwin, Petr Dusek and Anna Czlonkowska
19. Novel perspectives on Wilson disease treatment
Christian Rupp, Wolfgang Stremmel and Karl Heinz Weiss
20. Patient support groups in the management of Wilson disease
Michael L. Schilsky and Mary L. Graper

Anna Czlonkowska MD Prof earned her Diploma of Medicine at Warsaw Medical Academy before she completed her Doctor of Medicine at the Institute of Psychiatry and Neurology, Warsaw. She received additional training at the Boards of Clinical Neurology at the Institute of Psychiatry and Neurology in Warsaw and Habilitation in Neurology at the Warsaw Medical Academy. She has also received several prestigious fellowships, ranging from a British Council Grant for Neuroimmunology to a Neurobiology Fellowship funded by a Max Planck Society Grant. Between 1985-2013, she served as Professor and Head of the Second Department of Neurology at the Institute of Psychiatry and Neurology in Warsaw. She currently is the professor in this department and Head of the Study Group at the Department of Experimental and Clinical Pharmacology, Medical University of Warsaw. Additionally, Czlonkowska served as a member of the International Consortium at EUROWILSON. Since 1969, Czlonkowska has not only cared for a large cohort of 850 patients with Wilsons Disease, created a research database to document their clinical features and evaluate the clinical course of WD (with a focus on the efficacy of current therapies), but has also completed basic research on the pathogenesis of WD. She collaborates with WD centers across Europe.). Her contributions to clinical science extend well beyond Wilson's Disease and she has been active in research and clinical trials in stroke, multiple sclerosis and neurorehabilitation. Finally, Czlonkowska has supported the career development of many young clinicians and clinical academics whose success owes much to her leadership and support. Michael Schilsky, MD, became medical director of liver transplantation at Yale-New Haven Hospital in 2007, with appointments in medicine and surgery at the Yale School of Medicine. Dr. Schilsky received his medical degree from the University of Chicago, Pritzker School of Medicine. He completed his residency and fellowship in