Understanding Aging, Fatigue, and Inflammation

I Energy, evolution and medicine 1 Energy and the body.- 2 Evolutionary medicine.- 3 The brain and the immune system - two competing realms.- II Energy expenditure in the spotlight 4 Inflammation and energy.- 5 Pain and energy.- 6 Psychological stress and energy.- 7 Other energy-draining situations.- 8 What does increased energy expenditure mean for the body.- III From energy and evolution to symptoms 9 Daytime tiredness and depression.- 10 Sleep disorders and symptoms related to the time of day.- 11 Loss of appetite - malnutrition and malnutrition.- 12 Muscle wasting.- 13 Bone loss - osteoporosis.- 14 Weight changes (increase and decrease).- 15 Storage hormones (increase and decrease). 11 Loss of appetite, malnutrition and malnutrition.- 12 Muscle atrophy.- 13 Bone atrophy - osteoporosis.- 14 Weight changes (gain and loss).- 15 The storage hormone insulin doesn't do it - insulin resistance.- 16 Dwindling libido, lower fertility.- 17 The sympathetic nervous system fires the insulin hormone. 17 Sympathetic nervous system fires and causes high blood pressure.- 18 Increased blood clotting - thromboses/embolisms.- 19 Stress worsens inflammation and inflammation changes stress resilience.- 20 The big summary: unwanted energy expenditure.- Glossary.- Appendix.

Professor Dr. med. Rainer H. Straub is Professor of Experimental Medicine and Rheumatologist. He heads the Laboratory for Experimental Rheumatology and Neuroendocrine Immunology, Department of Internal Medicine at the University Hospital Regensburg.