Translational Stroke Research

Vascular Targets For Ischemic Stroke Treatment.- Identifying Vascular Targets to Treat Hemorrhagic Stroke.- Experimental Platforms For Assessing White Matter Pathophysiology In Stroke.- Neuroprotection in Stroke.- Protein Aggregation And Multiple Organelle Damage After Brain Ischemia.- Antioxidants And Stroke. Success And Pitfalls.- Caspase-Independent Stroke Targets.- Hypoxia-Inducible Factor: A New Hope To Counteract Stroke.- Thrombin in Ischemic Stroke Targeting.- Toll-Like Receptor Agonists As Antecedent Therapy For Ischemic Brain Injury: Advancing Preclinical Studies To The Nonhuman Primate.- Angiogenesis and Arteriogenesis As Stroke Targets.- Hematopoietic Growth Factor Family For Stroke Drug Development.- Soluble Epoxide Hydrolase As A Stroke Target.- Membrane Potential As Stroke Target.- Hypothermia To Identify Therapeutic Targets For Stroke Treatment.- Stroke Preconditioning To Identify Endogenous Protective Or Regenerative Mechanisms.- MicroRNAs in Ischemic Brain: The Fine-tuning Specialists and Novel Therapeutic Targets.- Neuroglobin: A Novel Target For Endogenous Neuroprotection.- Characterization Of Novel Neuroprotective Lipid Analogues For The Treatment Of Stroke.- Na+/H+ Exchangers As Therapeutic Targets For Cerebral Ischemia.- Iron as a therapeutic target in intracerebral hemorrhage: Preclinical testing of deferoxamine.- Overcoming Barriers To Translation From Experimental Stroke Models. Animal Models Of Stroke For Preclinical Drug Development: A Comparative Study Of Flavonols For Cytoprotection.- Clinical Relevance In A Translational Rodent Model Of Acute Ischemic Stroke: Incorporating The Biological Variability Of Spontaneous Recanalization.- A Clinically Relevant Rabbit Embolic Stroke Model For Acute Ischemic Stroke Therapy Development: Mechanisms & Targets.- Animal Models of Intracranial Aneurysm for treatment.- Animal Models of SAH and Their Translation toClinical SAH.- ADME (Absorption, Distribution, Metabolism, Excretion) - The Real

From the reviews:

"This book is an excellent review of cerebral hemorrhage, ischemia, and hypoxia as it involves pathology, pathophysiology, and cellular tolerance. It will appeal to a wide variety of investigators in stroke, neurology, and neurosurgery research. I highly recommend it in Neurology Research." (Joseph J. Grenier, Amazon.com, February, 2014)"In Translational Stroke Research, Lapchak and Zhang have gathered an impressive, and very large, assortment of clinicians and researchers from around the world to offer reports of their studies, new ideas ... and directions for future research based mainly on pleotropic and combined therapies. ... The authors are to be congratulated on a great effort in furthering the available information and pitfalls in this field and pointing researchers and practitioners in a clinically significant direction. ... It makes for fascinating reading!" (Elizabeth A. M. Frost, Journal of Neurosurgical Anesthesiology, Vol. 24 (4), October, 2012)