The Geometry of Biological Time

1. Circular Logic.- 2. Phase Singularities (Screwy Results of Circular Logic).- 3. The Rules of the Ring.- 4. Ring Populations.- 5. Getting off the Ring.- 6. Attracting Cycles and Isochrons.- 7. Measuring the Trajectories of a Circadian Clock.- 8. Populations of Attracting-Cycle Oscillators.- 9. Excitable Kinetics and Excitable Media.- 10. The Varieties of Phaseless Experience: In which the Geometrical Orderliness of Rhythmic Organization Breaks Down in Diverse Ways.- 11. The Firefly Machine.- 12. Energy Metabolism in Cells.- 13. The Malonic Acid Reagent ("Sodium Geometrate").- 14. Electrical Rhythmicity and Excitability in Cell Membranes.- 15. The Aggregation of Slime Mold Amoebae.- 16. Numerical Organizing Centers.- 17. Electrical Singular Filaments in the Heart Wall.- 18. Pattern Formation in the Fungi.- 19. Circadian Rhythms in General.- 20. The Circadian Clocks of Insect Eclosion.- 21. The Flower of Kalanchoë.- 22. The Cell Mitotic Cycle.- 23. The Female Cycle 650 A: Women, Hormones, and Eggs.- Index of Author Citations and Publications.- Index of Subjects.

From the reviews:

"This book is a wonderful exposition about his life's work and is presented with such clarity that the reader gains an insight into details of his manner of thinking...the reader is taken on a quest to solve biological mysteries and travels from the intricate beginnings of formulating the questions, through the apices and troughs of analyzing, and on to the discovery of the holy grail, that which yields biological predictions and answers. One leaves with a sense of understanding that hopefully can be applied to one's own work...this book could easily serve a dual purpose. First, through the introduction of basic mathematical concepts such as topology combined with modeling, the book serves as an introduction helping the non-applied reader to see the beauty of mathematical modeling. Second, because Winfree explains the modeling process very thoroughly, instead of just presenting equations, the book can serve as a medium for the medical professional to acquire an understanding of the modeling process. A wonderful accomplishment...I am proud to have this book on my shelf and consider it...a seminal text in mathematical modeling. This is a text that every first year graduate student should look at in some detail." (Mathematical Reviews)

"The new edition of The Geometry of Biological Time is a fascinating update of the delightful original. This new edition contains thoughtful commentary on new developments in the field, adding a historical and sociological dimension to the original book's elegant and unifying treatment of biological problems involving processes that repeat themselves regularly, i.e. involve 'rhythmic return through a cycle of change.' The book is an enjoyable page-turner, even for those readers with only a passing interest in biology, and demonstrates well the synergistic effect between biology and mathematics. ...
The term 'page-turner' may seem unusual in mathematics; however, it is appropriate here.Not only is