Synthesis and Biological Evaluation of N and S Based Heterocycles
New Synthetic Approaches to Nitrogen and Sulfur Based Heterocycles and Biological Assessment for Selected Analogs
(Sprache: Englisch)
Nitrogen and sulfur heterocycles are recognized as "privileged medicinal scaffolds" because these compounds are found in a wide variety of bioactive natural products and pharmaceuticals. Among them, azoles (1,2 and 1,3-azoles) have been considered as an...
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Nitrogen and sulfur heterocycles are recognized as "privileged medicinal scaffolds" because these compounds are found in a wide variety of bioactive natural products and pharmaceuticals. Among them, azoles (1,2 and 1,3-azoles) have been considered as an 'important structural motif' in a huge number of natural products and also in medicinally valuable compounds. Because of their broad based utility, efforts to develop green and sustainable synthetic methodologies for the synthesis of 1,2 and 1,3-azoles are on the ever-increasing trend in synthetic organic chemistry. In the present study, attempts have been made to develop new synthetic routes for the synthesis of benzo-fused 1,2-azoles (indazoles) and 1,3-azoles (benzimidazoles) and nitrogen and sulfur containing 1,3- azoles like thiazoles (i.e. 2-aminothiazoles and hydrazinyl-thiazoles). Further, biological activities (antioxidant, antimicrobial and anti-cancer) of the synthesized hydrazinyl-thiazole compounds have been investigated.
Autoren-Porträt von Gundala Trivikram Reddy, Nallagondu Chinna Gangi Reddy
Trivikram Reddy, GundalaDr. N.C. Gangi Reddy obtained PhD degree from Sri Venkateswara University, Tirupati, INDIA. Working as an Associate Professor in the Department of Chemistry, Yogi Vemana University, Kadapa. His research interests are i) Design and synthesis of D-A type small organic fluorescent materials and ii) Development of green synthetic methodologies.
Bibliographische Angaben
- Autoren: Gundala Trivikram Reddy , Nallagondu Chinna Gangi Reddy
- 2021, 192 Seiten, Masse: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6203861219
- ISBN-13: 9786203861211
Sprache:
Englisch
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