Pyrazolopyrimidines: Chemical Synthesis and Biological Activity
(Sprache: Englisch)
Heterocyclic compounds with nitrogen atom play a key role in the normal life cycle of a cell. Pyrazolopyrimidine is a privileged class of nitrogen containing fused heterocyclic compound contributing to a major portion of all lead molecules in medicinal...
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Heterocyclic compounds with nitrogen atom play a key role in the normal life cycle of a cell. Pyrazolopyrimidine is a privileged class of nitrogen containing fused heterocyclic compound contributing to a major portion of all lead molecules in medicinal chemistry. The thumbprint of pyrazolopyrimidine as a pharmacophore is always noticeable due to its analogy with the adenine base in DNA. Pyrazolopyrimidines are divided into five types [I, II, III, IV, V] based on the mechanism of action on the specific target conferring a wide scope of research which has accelerated the interest of researchers to investigate its biological profile. In 1956, the anti-cancer activity of pyrazolopyrimidine was evaluated for the first time with appreciable activity. Since then, medicinal chemists centered their work on various methods of synthesis and evaluating the biological profile of pyrazolopyrimidine isomers. This book consists of novel methodologies followed to synthesize pyrazolopyrimidine isomers along with a note on their anticancer activity.
Autoren-Porträt von Kaushik Chanda
Chanda, KaushikDr Kaushik Chanda, obtained his PhD in Applied Chemistry from National Chiao Tung University, Taiwan and is working as Assistant Professor Sr in the Department of Chemistry, Vellore Institute of Technology Vellore, India. He has published more than 50 international peer reviewed journal articles, four book chapters, and one US,two Indian patent.
Bibliographische Angaben
- Autor: Kaushik Chanda
- 2020, 152 Seiten, Masse: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6202525282
- ISBN-13: 9786202525282
Sprache:
Englisch
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