Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions

Chapter 1. Molecular and Infection biology of M. tuberculosis.- Chapter 1.1. The new knowledge on the PE_PGRS proteins, eventually extending the summary on PE/PPE.- Chapter 1.2. The PE and PPE family proteins of mycobacteria: What they are upto?- Chapter 1.3. Co-operonic and non-co-operonic PE-PPE genes and their function.- Chapter 1.4. Methyltransferases of Mycobacterium tuberculosis.- Chapter 1.5. Heat shock proteins as drug target.- Chapter 1.6.  Poly- -L-glutamine: a multifunctional molecule in mycobacterial cell wall contributes to biofilm formation, virulence and cell wall integrity.- Chapter 1.7. Celluar stress responses and immunological regulations during M. Tuberculosis infection.- Chapter 2. Pathology and Epidemiology of Tuberculosis-. Chapter 2.1. Nontuberculous mycobacteria as emerging pathogens: challenges in diagnostics, treatment and pathogenicity research.- Chapter 2.2. Mesenchymal stem cells: A hidden arsenal for M.tuberculosis  persistence, resuscitation and reactivation.- Chapter 2.3. Charting the patho-epidemiological interconnectivity between tuberculosis and non-communicable disease.- Chapter 2.4. MDR-TB in Australia and cross-border spread of strains.- Chapter 3. Vaccines, Diagnostics and Clinics.- Chapter 3.1. TB Vaccine: Present and Future Perspective.- Chapter 3.2. Role of nanotechnology in improving M. tuberculosis diagnosis sensitive, faster, cheaper and deployable.- Chapter 3.3. Best Practices in M. tuberculosis Research.

Prof Seyed E. Hasnain has contributed significantly to tuberculosis research focusing on infection biology and functional epidemiology. He has received numerous recognitions and honors including, Robert Koch Fellow, Berlin; Fellow, American Academy of Microbiology (USA); Member, German National Academy of Sciences-Leopoldina; Fellow, TWAS (Italy), and Fellow of all the major Indian Science Academies (FNA/FASc/FNASc). He also received the Alexander von Humboldt Research Award (Germany), Shanti Swarup Bhatnagar Prize, GD Birla Award, JC Bose Fellowship and many others. A former member of the Science Advisory Council to the Prime Minister of India for 2 terms (2004-2014), Hasnain was the first Director of the Centre for DNA Fingerprinting and Diagnostics, Hyderabad and later Vice-Chancellor of the prestigious University of Hyderabad (2005-2011) and served as invited Professor, IIT-Delhi (2011-2019). Currently, he is the Vice-Chancellor of Jamia Hamdard and also Professor, JH-Institute of Molecular Medicine, where he leads a very large, active and generously funded TB research group.