Mitochondrial Disorders

- Introduction

I. Mitochondrial Biology:
1. The Mitochondrial Machinery
2. Mitochondria in Neurodegeneration
3. Apoptosis and Oxidative Stress in Mitochondrial Disorders
4. Mitochondria and Ageing
5. Cardiac Mitochondrial Dysfunction in Ageing and in Ischemia/Reperfusion. Role of Oxygen Free Radicals and Cardiolipin
6. Deregulation of Mitochondrial Apoptosis in Cancer

II. Iatrogenic Mitochondrial Diseases:
7. Drug Induced Hepatotoxicity and Mitochondrial Dysfunction
8. The Carnitine System Involvement in Mitochondrial Pharmacologic Sensitivity
9. Mitochondrial Toxicity of Antiretroviral Drugs
10. Mitochondrial Damage in HIV Patients Treated with Highly Active Antiretroviral Therapy
11. Hyperlactatemia and HIV-infected Patients with Nucleoside Analog Reverse-Transcriptase Inhibitors Treatment: The Clermont HIV Cohort Study
12. Severe Lactic Acidosis and Multiple Organ Failure in HIV Patients Treated with Nucleoside Analogues Reverse Transcriptase Inhibitors: A Pilot Study of Treatment with L-Carnitine
13. Mitochondrial Dysfunction in Perinatal Exposure to Antiretroviral Nucleoside Analogues
14. Mitochondrial Myopathy in Non-infected New-Born from HIV-1 Mothers Treated with Antiretroviral Drugs

III. Mitochondrial Medicine:
15. Neurological Features of Genetic and Acquired Metabolic Mitochondrial Defects
16. Clinical Heterogeneity Associated to Dysfunction of Mitochondrial DNA: The example of the 3243 MELAS Mutation
17. Inborn and Acquired Mitochondrial Leucodystrophy
18. Mitochondrial Dysfunction, Epilepsy, and Antiepileptic drugs
19. Friedreich Ataxia as an Example of the Dual Genome Control of Mitochondrial Function
20. How Wide are Mitochondria Involved in Exercise Intolerance?
21. Mitochondrial Defects in Myositis and Inclusion Body Myopathies
22. Mitochondrial Dysfunction and the Gastrointestinal System
23. Mitochondrial Diabetes: Clinical Specificity and Diagnosis
24. Mitochondrial Featuring in Kidney Disorders and