High Density Lipoproteins, Dyslipidemia, and Coronary Heart Disease

1. Introduction to HDL, Dyslipidemia, and Coronary Heart Disease2. Regulation of Apolipoprotein A-I Gene Expression, Synthesis, and Function3. The Many and Varied Functions of HDL4. HDL Particle Composition, Proteomics, and Metabolism5. HDL Structure, Function, and Anti-inflammatory Properties6. Human ApoA-I Deficiency7. Human ApoA-I Variants8. Cellular Cholesterol Efflux 1: ABCA 1 Function and Deficiency9. Cellular Cholesterol Efflux 2: ABCG1 Function10. Cellular Cholesterol Efflux 3: ABCA1, ABCG1 and HDL Particle Interaction11. Cholesterol Esterification and Human LCAT Deficiency12. Effects of Lipoprotein Lipase and Hepatic Lipase Deficiency on HDL Metabolism13. Cholesteryl Ester Transfer Protein (CEPT) and Human CETP Deficiency14. HDL Metabolism and Scavenger Receptor B115. The Genetics of HDL16. Effects of Nutrition and Excersize on HDL Metabolism17. Effects of Alcohol on HDL Metabolism18. Effects of Estrogens on HDL Metabolism19. Efects of Niacin on HDL Metabolism20. Effects of Statins on HDL Metabolism21. Effects of Fibrates on HDL Metabolism22. Effects of Cholesterol Ester Transfer Protein Inhibition on HDL Metabolism23. Oral and HDL Infusion Therapy to Enhance Reverse Cholesterol Transport24. Conclusions