Executive Control and the Frontal Lobe: Current Issues

While the importance of the prefrontal cortex for "higher-order" cognitive functions is largely undisputed, no consensus has been reached regarding precise specifications of these functions. For example, although some degree of regional specialization within the frontal lobe seems inevitable, by and large, most attempts to map specific cognitive functions onto neuroanatomical and/or cytoarchitectonic subdivisions have been disappointing. Although a high degree of functional specialization probably exists within the frontal cortex, it seems increasingly likely that the structural organization of this system does not relate, in any straightforward way, to contemporary models of cognition. While the importance of the prefrontal cortex for 'higher-order'cognitive functions is largely undisputed, no consensus has been reached regarding the precise fractionation of these functions. For example, although some degree of regional specialization within the frontal lobe seems inevitable, to date, most attempts to map specific cognitive functions onto neuroanatomical and/or cytoarchitectonic sub-divisions have been disappointing. The chapters in this volume are based on the workshop on "Executive Control and the Frontal Lobe: Current Issues"at the Hanse Institute for Advanced Study in Delmenhorst, Germany and, accordingly, most of the methodological approaches and theoretical positions within the field are well represented. Accordingly, several of the authors have focussed on behavioural and/or imaging data acquired from patients with discrete frontal-lobe lesions, while others have described the results of lesion studies in the monkey which attempt to shed light on both the anatomical and functional organisation of the prefrontal cortex. Several complimentary chapters have considered functional studies of frontal-lobe functions in healthy control volunteers, either through meta-analysis or by focussing on specific aspects of working memory, motor planning and programming or