Cellular Senescence and Tumor Suppression
(Sprache: Englisch)
This book covers the latest findings in the link between cellular senescence and cancer including telemores and senescence signals, the senescent phenotype, and the physiological effects of senescence, including therapeutic applications.
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Produktinformationen zu „Cellular Senescence and Tumor Suppression “
This book covers the latest findings in the link between cellular senescence and cancer including telemores and senescence signals, the senescent phenotype, and the physiological effects of senescence, including therapeutic applications.
Klappentext zu „Cellular Senescence and Tumor Suppression “
As cells mature they naturally stop dividing and enter a period called senescence. But cellular senescence can also be induced prematurely by certain oncogenes involved in cancer development. Cellular senescence, a growth-arrest program that limits the lifespan of mammalian cells and prevents unlimited cell proliferation, is attracting considerable interest because of its links to tumor suppression.
Inhaltsverzeichnis zu „Cellular Senescence and Tumor Suppression “
- Introduction: J SedivySection 1. Senescence signals
1. Telomere biology and biochemistry: 1, J Karlseder; 2, T de Lange; 3, L Harrington
2. Short telomere-driven senescence: 1, F d'Adda di Fagagna; 2, N Sharpless; 3, V Bohr
3. Oncogene-induced senescence: 1, M Serrano; 2, J Bartek; 3, G, Ferbeyre
4. Stress-induced senescence: 1, T Finkel; 2, V Gorbunova; 3, E Hara; 4, F Ishikawa
5. Modulation of senescence by extracellular growth factors: 1, P Adams. Section 2. The senescent phenotype
6. The senescent phenotype and its evolution: 1, J Campisi
7. Chromatin structure in senescent cells: 1, E Medrano; 2. M Narita
8. A comparison of senescence in mouse and human cells: 1, C Greider; 2, M Blasco. Section 3. The physiological consequences of senescence
9. Tumor suppression: 1, G Peters; 2, N Sharpless; 3, S Chang
10. Tissue aging: 1, L Rudolph; 2, A Trumpp
11. Senescence as a potential therapeutic tool: 1, C Schmitt; 2, S Lowe
Bibliographische Angaben
- 2014, 2010, XIII, 272 Seiten, 272 farbige Abbildungen, Masse: 15,5 x 23,5 cm, Kartoniert (TB), Englisch
- Herausgegeben: Peter D. Adams, John M. Sedivy
- Verlag: Springer, Berlin
- ISBN-10: 1489983562
- ISBN-13: 9781489983565
Sprache:
Englisch
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