Cancer Drug Discovery and Development / Insulin-like Growth Factors and Cancer
From Basic Biology to Therapeutics
(Sprache: Englisch)
This book explores the insulin-like growth factor system and its vital role in cancer development and progression. Covers biology, epidemiology and the therapeutic potential of inhibiting receptors using newly discovered antibodies and kinase inhibitors.
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Produktinformationen zu „Cancer Drug Discovery and Development / Insulin-like Growth Factors and Cancer “
This book explores the insulin-like growth factor system and its vital role in cancer development and progression. Covers biology, epidemiology and the therapeutic potential of inhibiting receptors using newly discovered antibodies and kinase inhibitors.
Klappentext zu „Cancer Drug Discovery and Development / Insulin-like Growth Factors and Cancer “
The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.
Inhaltsverzeichnis zu „Cancer Drug Discovery and Development / Insulin-like Growth Factors and Cancer “
Preface.- Epidemiology of IGF-1 and Cancer.- Aging and Cancer: The IGF-I Connection.- Obesity, Type 2 Diabetes and Cancer.- IGF System and Breast Cancer.- The Role of Insulin-Like Growth Factor Signaling in Prostate Cancer Development and Progression.- Mouse Models of IGF-1 Deficiency.- Insulin-like Growth Factor Signaling in Pediatric Sarcomas.- Cancer Genes, Tumor Suppressors, and Regulation of IGF-1R Expression in Cancer.- Mouse Models of IGF-1R and Cancer.- Targeting the Insulin-Like Growth Factor-I Receptor in Cancer Therapy.- Targeting Insulin-like Growth Factor (IGF-1R) and Insulin Receptor Signaling by Tyrosine Kinase Inhibitors in Cancer.- Calories and Cancer: The Role of Insulin-like Growth Factor.- Cancer Cell Metabolism.- Overlaps between the Insulin and IGF-1R and Cancer.- Index
Bibliographische Angaben
- 2013, 2012, XII, 284 Seiten, Masse: 15,5 x 23,5 cm, Kartoniert (TB), Englisch
- Herausgegeben: Derek Leroith
- Verlag: Springer, Berlin
- ISBN-10: 1461429625
- ISBN-13: 9781461429623
Sprache:
Englisch
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