The Human Genome

PART I: HOW GENES SPECIFY A TRAIT
1: The Basics of Heredity: How Traits Are Passed Along in Families
2: The Double Helix: How Cells Preserve Genetic Information

PART II: HOW GENES FUNCTION
3: The Central Dogma of Molecular Biology: How Cells Orchestrate the Use of Genetic Information
4: The Genetic Code: How the Cell Makes Proteins from Genetic Information Encoded in mRNA Molecules
5: We Are All Mutants: How Mutation Alters Function

PART III: HOW CHROMOSOMES MOVE
6: Mitosis and Meiosis: How Cells Move Your Genes Around
7: The Odd Couple: How the X and Y Chromosomes Break the Rules
PART IV: HOW GENES CONTRIBUTE TO COMPLEX TRAITS
8: Sex Determination: How Genes Determine a Developmental Choice
9: Complexity: How Traits Can Result from Combinations of Factors
10: The Multiple-Hit Hypothesis: How Genes Play a Role in Cancer

PART V: HOW GENES ARE FOUND
11: The Gene Hunt: How Genetic Maps Are Built and Used
12: The Human Genome: How the Sequence Enables Genome-wide Studies

PART VI: HOW GENES PLAY A ROLE IN TESTING AND TREATMENT
13: Genetic Testing and Screening: How Genotyping Can Offer Important Insights
14: Magic Bullets: How Gene-based Therapies Personalize Medicine
15: Fears, Faith, and Fantasies: How the Past and Present Shape the Future of Genomic Medicine

Julia E. Richards (PhD, Genetics, University of Wisconsin) is Professor of Ophthalmology and Visual Sciences and Professor of Epidemiology at the University of Michigan in Ann Arbor where she teaches introductory genetics to graduate students in the School of Public Health. She is widely known for her research on inherited eye diseases and has published numerous chapters and research articles focused on human genetics.

"Written to communicate sound and modern science in an accessible way for professionals and students with various levels of scientific background, this thoroughly revised edition of The Human Genome contributes to creating a genetically literate research and clinical population."--ANTICANCER RESEARCH 33: 745-746 (2013), February 2013 "Every year, Choice subject editors single out for recognition the most significant print and electronic works reviewed in Choice during the previous calendar year. The Human Genome, 3e, appearing annually in Choice's January issue, this prestigious list of publications reflects the best in scholarly titles and attracts extraordinary attention from the academic library community. The 2011 feature includes 629 titles in 54 disciplines and subsections."--CHOICE Outstanding Academic Title, 2011 "Well written, up-to-date, and engaging, this new edition of The Human Genome (2nd ed., 2005; 1st ed., CH, May'99, 36-5066) by Richards (Univ. of Michigan) and Hawley (Stowers Institute for Medical Research) accurately reflects its subtitle. Densely packed with information, it is both easy to read and easy to understand. It includes full-color illustrations, charts, drawings, and tables. Case studies and sidebar interest boxes tell fascinating stories that capture the reader's interest and help make the material accessible to all. End-of-chapter study questions include brief essays and ideas for resource projects. A companion Web site provides additional questions, and indicates that an image bank and streaming video resources will soon be available. This work could easily be used for a freshman biology class or for individual reading for people interested in this subject. Yet, it has enough technical information and detail to be useful for an upper-level majors class in human genetics as well. It addresses all of the topics traditionally covered in a human genetics textbook without reading like a textbook. It strikes a perfect balance between being