Reducing Mortality in Acute Kidney Injury

Preface.- Part I. Introduction.- Acute Kidney Injury: the plague of the new millennium.-  Acute Kidney Injury: Definitions, Incidence, Diagnosis, and Outcome.- Reducing mortality in acute kidney injury: the democracy-based approach to consensus.- Part II. Interventions that May Reduce Mortality.- Continuous renal replacement therapy vs. intermittent hemodialysis: impact on clinical outcomes.- May an "early" renal replacement therapy improve survival?.- Increased intensity of renal replacement therapy to reduce mortality in patients with acute kidney injury.- Citrate anticoagulation to reduce mortality in patients needing continuous renal replacement therapy.- Peri-angiography hemofiltration to reduce mortality.- Continuous venovenous hemofiltration to reduce mortality in severely burned patients.- Perioperative hemodynamic optimization to reduce acute kidney injury and mortality in surgical patients.- Furosemide by continuous infusion to reduce mortality in patients with acute kidney injury.- N-acetylcysteine to Reduce Mortality in Cardiac Surgery.- Fenoldopam and Acute Kidney Injury. Is it time to turn the page?.-Vasopressin to reduce mortality in patients with septic shock and acute kidney injury.- Terlipressin reduces mortality in hepatorenal syndrome.- Albumin to reduce mortality in cirrhotic patients with acute kidney injury.- Extracorporeal Removal of Serum Free Light Chains in Patients with Multiple-Myeloma Associated Acute Kidney Injury.- Can intravenous human immunoglobulins reduce mortality in patients with (septic) acute kidney injury?.- Part III. Interventions that May Increase Mortality.- Fluid overload may increase mortality in patients with Acute Kidney Injury.- Hydroxyethyl starch, acute kidney injury, and mortality.- Loop diuretics and mortality in patients with acute kidney injury.- Part IV. Update.- Reducing Mortality in Patients with Acute Kidney Injury: A Systematic Update.

Giovanni Landoni is currently Associate Professor at Vita-Salute San Raffaele University, Milan, where he works as Head of Research in the Department of Anesthesia and Intensive Care, San Raffaele Scientific Institute. Dr. Landoni is the Italian member of the Representative Council of the European Association of Cardiothoracic Anesthesiologists (EACTA, 2012-17). He is a past Vice-President of the Italian Association of Cardiothoracic Anesthesiologists (ITACTA) and a member of the ECMO team of San Raffaele Scientific Institute. He is a member of the editorial boards of several international journals and his strong clinical and research interests in intensive care and anesthesia have resulted in more than 400 scientific publications, including more than 250 in indexed journals (as at March 2016 he has an H index of 31).


Antonio Pisano is staff anesthesiologist and intensivist at the Cardiac Anesthesia and Intensive Care Unit of the Monaldi High Specialty and University Hospital, A.O. "Dei Colli", Naples, Italy. His scientific contributions include, among others, papers published in the Journal of the American Medical Association and in Critical Care Medicine. He is the author of several book chapters in the fields of anesthesiology, critical care medicine, and non-invasive ventilation. Currently, he is principal investigator in several multicenter randomized trials and he collaborates with various international journals as a reviewer.


Alberto Zangrillo is Full Professor in Anesthesiology and Intensive Care and Head of Anesthesia and Intensive Care at San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy, the largest Italian surgical hospital. Dr. Zangrillo is among the world's top 10 fastest publishing clinical scientists in the field of anesthesia and is the author of more than 500 scientific publications on intensive care (H index of 30). He has participated as principal investigator

"This brief monograph describes medications and treatment strategies for patients with acute kidney injury in the critical care setting. ... Clinicians in disciplines supporting critical care units including anesthesiology, internal medicine, and surgery are an appropriate audience for this book, as are renal specialists working in the intensive care unit. ... Citations for all key papers are included with each chapter." (David J. Dries, Doody's Book Reviews, September, 2016)